The antibiotic resistance gene | ||||

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Lai, L., J. Dai, H. Tang, S. Zhang, C. Wu, W. Qiu, C. Lu, H. Yao, H. Fan, and Z. Wu. (2017). Streptococcus suis serotype 9 strain GZ0565 contains a type VII secretion system putative substrate EsxA that contributes to bacterial virulence and a vanZ-like gene that confers resistance to teicoplanin and dalbavancin in Streptococcus agalactiae. Vet Microbiol 205: 26-33. | ||||

Woods, E.C., D. Wetzel, M. Mukerjee, and S.M. McBride. (2018). Examination of the Clostridioides (Clostridium) difficile VanZ ortholog, CD1240. Anaerobe. [Epub: Ahead of Print] | ||||

Examples: | ||||

TC# | Name | Organismal Type | Example | |

2.A.128.1.1 | The 4 TMS VanZ MDR export system confers resistance to teicoplanin and dalbavancin in | VanZ of | ||

2.A.128.1.10 | VanZ homologue of 224 aas and 6 TMSs | VanZ homologue of | ||

2.A.128.1.11 | VanZ family proteinof 122 aas and 4 TM | VanZ of | ||

2.A.128.1.12 | Teicoplanin resistance protein VanZ of 120 aas and 4 TMSs. | VanZ of | ||

2.A.128.1.13 | VanZ family proteinof 204 aas and 5 TMSs | VanZ of | ||

2.A.128.1.14 | VanZ family proteinof 125 aas and 4 TM | VanZ of | ||

2.A.128.1.15 | Uncharacterized protein of 247 aas and 8 TMSs, where the first 4 TMSs are homologous to VanZ proteins | UP of | ||

2.A.128.1.16 | VanZ family proteinof 119 aas and 4 TMSs. | VanZ of | ||

2.A.128.1.17 | VanZ like family proteinof 118 aas and 4 TM | VanZ of | ||

2.A.128.1.18 | VanZ like family proteinof 270 aas and 4 central TM | VanZ of Colletotrichum nymphaeae | ||

2.A.128.1.19 | VanZ family protein of 202 aas and 5 TMSs in a 1 + 2 + 2 arrangement. | VanZ of | ||

2.A.128.1.2 | VanZ homologue of 210 aas and 5 TMSs. | VanZ of | ||

2.A.128.1.20 | Teicoplanin resistance protein, VanZ1 of 169 aas and 5 (or 6) putative TMSs in a 1 + 4 arrangement (or in a 6 TMS arrangement). Its synthesis is induced by the antiicrobial peptide, LL-37 (1.C.33.1.10), but not by many other antimicrobials tested (Woods | VanZ1 of | ||

2.A.128.1.3 | VanZ homologue of 181 aas and 5 TMSs | VanZ of | ||

2.A.128.1.4 | VanZ homologue of 143 aas and 4 TMSs | VanZ of | ||

2.A.128.1.5 | VanZ/RDD domain protein of 386 aas and 9 TMSs | VanZ/RDD protein of | ||

2.A.128.1.6 | VanZ homologue of 243 aas and 5 TMSs. | VanZ of | ||

2.A.128.1.7 | VanZ homologue of 162 aas and 4 TMSs. | VanZ of | ||

2.A.128.1.8 | VanZ homologue of 202 aas and 5 TMSs | VanZ of | ||

2.A.128.1.9 | VanZ homologue of 436 aas and 7 TM | VanZ of | ||

Examples: | ||||

TC# | Name | Organismal Type | Example | |

2.A.128.2.1 | VanZ family protein of 163 aas and 4 TM | VanZ of | ||

2.A.128.2.2 | Teicoplanin resistance protein, VanZ of 164 aas and 3 or 4 TMSs. | VanZ of | ||

2.A.128.2.3 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase of 743 aas and an N-terminal hydrophobic domain with 4 TMSs that are homologous to VanZ family members. | N-terminal VanZ domain protein of | ||

2.A.128.2.4 | VanZ family proteinof 135 aas and 4 TMSs. | VanZ of | ||

2.A.128.2.5 | Uncharacterized proteinof 203 aas and 6 TMSs. | UP of | ||

2.A.128.2.6 | VanZ family protein of 129 aas andd 4 TMSs | VanZ of | ||

2.A.128.2.7 | VanZ like family proteinof144 aas and 4 TMSs. | VanZ of | ||

2.A.128.2.8 | VanZ family protein of 158 aas and 4 TMSs. | VanZ of | ||