2.B.73. The Calix[4]Pyrrole Derivative Facilitator (CPDF) Family Calix[4]pyrrole derivatives function in the sensing of creatinine and the facilitated transmembrane transport of anions and amino acids (Escobar et al. 2023). Calix[4]pyrrole receptors provide model systems for the quantification of anion-pi interactions and the hydrophobic effect. Calix[4]pyrrole scaffolds have been applied to the development of molecular sensors, ionophores, transmembrane carriers, supramolecular protecting groups and molecular containers modulating chemical reactivity (Escobar et al. 2023).
This family belongs to the Calix[4]Pyrrole Superfamily.
References:
Escobar, L., Q. Sun, and P. Ballester. (2023). Aryl-Extended and Super Aryl-Extended Calix[4]pyrroles: Design, Synthesis, and Applications. Acc Chem Res. [Epub: Ahead of Print]