9.B.248. The DUF2070 (DUF2070) Family 

Proteins of this family have a variety of topologies, usually from 5 to 10 TMSs with all but one in the N-terminal part of the protein and one near the C-terminus.  These proteins may be oligosaccharyl transferases, resembling archaeosortase A system-associated proteins Almost all members of this family are found in archaea.


Examples:

TC#NameOrganismal TypeExample
9.B.248.1.1

DUF2070 family protein of ~ 8 TMSs.

DUF2070 family protein of Haloquadratum walsbyi

 
9.B.248.1.2

Uncharacterized membrane protein of 521 aas and 5 TMSs, 4 N-terminal and 1 C-terminal.

UP of Candidatus Nitrosoarchaeum koreensis MY1

 
9.B.248.1.3

Uncharacterized protein of 575 aas and 7 TMSs with 6 N-terminal and 1 C-terminal.

UP of Thermoplasma volcanium

 
9.B.248.1.4

DUF2070 domain-containing uncharacterized protein of 579 aas and 8 TMSs with 7 N-terminal and 1 C-terminal TMSs.

UP of Vulcanisaeta thermophila

 
9.B.248.1.5

Uncharacterized DUF2070 domain-containing proteinof 534 aas and 4 - 6 N-terminal TMSs plus 1 C-terminal TMS.

UP of Metallosphaera sedula

 
9.B.248.1.6

Arabinosyltransferase, AftA, of 650 aas and 13 TMSs in a 3 + 5 + 1 +4 arrangement.

AftA of Gordonia sihwensis

 
9.B.248.1.7

DUF2070 domain-containing proteinof 547 aas and 7 TMSs with 6 N-terminal and 1 C-terminal.

DUF2070 of Halostagnicola larsenii