9.B.252.  The Peptidase from Archaea and Bacteria-6 (PAB6) Family

The proteins in this familyl are of ~ 190 - 250 aas in length and have at least 5 TMSs, but some have more. They are all from bacteria and archaea and are very diverse in sequence.  Some members of the family are prepilin peptidases and are homologous to peptidases in TC families 1.A.54, 3.A.11, 3.A.15 and 9.B.1, 9.B.29, and 9.B.220, all members of the CAAX protease superfamily in TCDB. Therefore, these proteins are members of the CAAX Protease Superfamily.



This family belongs to the CAAX Superfamily.

Examples:

TC#NameOrganismal TypeExample
9.B.252.1.1

Uncharacterized protein of 206 aas and 5 TMSs.

UP of Candidatus Wolfebacteria bacterium

 
9.B.252.1.2

Uncharacterized protein of 220 aas and 5 TMSs

UP of the Parcubacterial group

 
9.B.252.1.3

Uncharacterized protein of 220 aas and 5 - 7 TMSs

UP of Candidatus Kaiserbacteria bacterium

 
9.B.252.1.4

Uncharacterized protein of 246 aas and 6 TMSs.

UP of Candidatus Terrybacteria bacterium

 
9.B.252.1.5

Uncharacterized protein of 203 aas and 5 TMSs

UP of Candidatus Azambacteria bacterium

 
9.B.252.1.6

Uncharacterized protein of 216 aas and 6 TMSs

UP of Candidatus Giovannonibacteria bacterium

 
Examples:

TC#NameOrganismal TypeExample
9.B.252.2.1

Uncharacteerized protein of 223 aas and 5 TMSs.

UP of Candidatus Jorgensenbacteria bacterium

 
9.B.252.2.2

Uncharacterized protein of 197 aas and 6 TMSs.

UP of Candidatus Harrisonbacteria bacterium

 
9.B.252.2.3

Uncharacterized protein of 216 aas and 6 TMSs.

UP of Candidatus Harrisonbacteria bacterium

 
Examples:

TC#NameOrganismal TypeExample
9.B.252.3.1

Uncharacterized protein of 204 aas and 5 TMSs.  This protein shows substantial sequence similarity with type 4 prepilin-like protein leader peptide-processing enzymes including those listed under TC#s 3.A.11.1.5 and 1.3, 3.A.15.1.1, 2.1 and 3.1, 9.B.220.1.2, 9.B.252.3.1 and 1.A.54.5.3. Thus, it is likely to be an integral membrane peptidase/protease.

UP of Candidatus Nealsonbacteria bacterium

 
9.B.252.3.2

Uncharacterized protein of 192 aas and 5 TMSs.

UP of Candidatus Berkelbacteria bacterium

 
9.B.252.3.3

Type 4 prepilin-like protein leader peptide-processing enzyme of 219 aas and 6 TMSs in a 2 + 4 arrangement. 

Peptidase of Candidatus Daviesbacteria bacterium

 
9.B.252.3.4

Putative type IV leader peptidase/N-methyltransferase of 299 aas and 8 TMSs.

Peptidase of Candidatus Daviesbacteria bacterium

 
9.B.252.3.5

Uncharacteerized protein of 200 aas and 5 TMSs

UP of Candidate division CPR2 bacterium

 
9.B.252.3.6

Uncharacterized protein of 272 aas and 8 TMSs.

UP of Parcubacteria bacterium

 
9.B.252.3.7

DUF996 domain-containing protein of 324 aas and 5 TMSs.

UP of Thermococcus eurythermalis

 
Examples:

TC#NameOrganismal TypeExample