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|---|---|
| Accession Number: | P02943 |
| Protein Name: | LamB aka MALB aka B4036 |
| Length: | 446 |
| Molecular Weight: | 49912.00 |
| Species: | Escherichia coli [83333] |
| Number of TMSs: | 1 |
| Location1 / Topology2 / Orientation3: | Cell outer membrane1 / Multi-pass membrane protein2 |
| Substrate | alpha-cyclodextrin, maltose, maltose, alpha-maltotriose, maltotetraose, antimicrobial agent, maltoheptaose heptasaccharide, maltopentaose pentasaccharide |
Cross database links:
| DIP: | DIP-10082N |
|---|---|
| RefSeq: | AP_004537.1 NP_418460.1 |
| Entrez Gene ID: | 948548 |
| Pfam: | PF02264 |
| BioCyc: | EcoCyc:EG10528-MONOMER ECOL168927:B4036-MONOMER |
| KEGG: | ecj:JW3996 eco:b4036 |
Gene Ontology
GO:0009279
C:cell outer membrane
GO:0005886
C:plasma membrane
GO:0046930
C:pore complex
GO:0015288
F:porin activity
GO:0005515
F:protein binding
GO:0005351
F:sugar:hydrogen symporter activity
GO:0009597
P:detection of virus
GO:0046718
P:entry of virus into host cell
GO:0006811
P:ion transport
GO:0015768
P:maltose transport
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References (16)[1] “Gene sequence of the lambda receptor, an outer membrane protein of E. coli K12.” Clement J.M.et.al. 6086106 [2] “Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.” Blattner F.R.et.al. 8265357 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Sequence determinants in the lamB gene of Escherichia coli influencing the binding and pore selectivity of maltoporin.” Heine H.G.et.al. 3301537 [6] “DNA sequence encoding the signal peptide of the lambda receptor in E. coli K 12.” Clement J.M.et.al. 161974 [7] “DNA sequence encoding the NH2-terminal peptide involved in transport of lambda receptor, an Escherichia coli secretory protein.” Hedgpeth J.et.al. 6446717 [8] “Genetic analysis of sequences in maltoporin that contribute to binding domains and pore structure.” Heine H.G.et.al. 2832377 [9] “Role of a disulfide bond in the thermal stability of the LamB protein trimer in Escherichia coli outer membrane.” Luckey M.et.al. 1988451 [10] “Permissive sites and topology of an outer membrane protein with a reporter epitope.” Charbit A.et.al. 1702781 [11] “A model of maltodextrin transport through the sugar-specific porin, LamB, based on deletion analysis.” Klebba P.E.et.al. 7925308 [12] “Sucrose transport through maltoporin mutants of Escherichia coli.” Van Gelder P.et.al. 11742115 | |
| Structure: | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MMITLRKLPL AVAVAAGVMS AQAMAVDFHG YARSGIGWTG SGGEQQCFQT TGAQSKYRLG 61: NECETYAELK LGQEVWKEGD KSFYFDTNVA YSVAQQNDWE ATDPAFREAN VQGKNLIEWL 121: PGSTIWAGKR FYQRHDVHMI DFYYWDISGP GAGLENIDVG FGKLSLAATR SSEAGGSSSF 181: ASNNIYDYTN ETANDVFDVR LAQMEINPGG TLELGVDYGR ANLRDNYRLV DGASKDGWLF 241: TAEHTQSVLK GFNKFVVQYA TDSMTSQGKG LSQGSGVAFD NEKFAYNINN NGHMLRILDH 301: GAISMGDNWD MMYVGMYQDI NWDNDNGTKW WTVGIRPMYK WTPIMSTVME IGYDNVESQR 361: TGDKNNQYKI TLAQQWQAGD SIWSRPAIRV FATYAKWDEK WGYDYTGNAD NNANFGKAVP 421: ADFNGGSFGR GDSDEWTFGA QMEIWW