Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.6.1.14
FMRFamide (peptide)-gated ionotropic receptor Na+ channel, NaC2-4 or NaC2, 3 and 5 (gated by neuropeptides Hydra-RFamides I and II; present in tentacles) (Golubovic et al. 2007). Three homologous subunits, NaC2, 3 and 5, assemble to form a more typical high affinity peptide-gated ion channel (Durrnagel et al., 2010).

Accession Number:A8DZR6
Protein Name:Hydra Na channel 2
Length:469
Molecular Weight:53902.00
Species:Hydra magnipapillata (Hydra) [6085]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Secreted1
Substrate

Cross database links:

Pfam: PF00858   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005272 F:sodium channel activity
GO:0006814 P:sodium ion transport

References (1)

[1] “A peptide-gated ion channel from the freshwater polyp hydra.”  Golubovic A.et.al.   17911098

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MKARFARRME KIVEERMTVK QIFNRYVQTS TLHGFRFIFM DTFIVRRVLW TILTLTMATI 
61:	FFKELRNSIN LFYEYPFTTT STIQYEPSLT FPAISVCNLN HFLLSKIKKS KLKPLYDQGR 
121:	LPFDNNLENP GFDIQGEELY SILKTSSQSI DEIFLSCEWK SRDTAKNGVP NPCKPNNFTV 
181:	YSGLYGQSCY TFNPGVSGYP LLSLSETGVN MGFKLELDLK SKDSLQGIQE IGAIVIVHHQ 
241:	QETPVLQAGF VVSPGFQTFV EIKVRQTENL PPPYATKCGS KPLKNYQIYR QSSCFLEQLG 
301:	DAIETKCKCK SSFMAGRNIP YCSLRQTVTC LMPTIYDFDR KTNNNCPVDC ETIQYLSSLS 
361:	YARFISNVTY LSKNAEQSSY IRKLKNSMSP KKLQKYIEEN IVAVQFFYQE MKKEKVKQEP 
421:	SYDFYKLIGD VGGQLGLLLG ASVLTLVEFV DLFIFTLYHQ LLRLSKKKS