9.A.63.1.2
Core of the retromer-mediated endocytic recycling complex, Vps35 (852 aas)-Vps26 (268 aas)-Vps29 (203 aas); mediates retrograde transport that is
essential for parasite integrity and host infection (Sangaré et al. 2016). Signaling defect in vps26 mutants may be the result of impaired Notch signaling based on the misexpression of multiple proteins in the Notch signaling pathway in vps26 mutants (Starble and Pokrywka 2018).
|
| Accession Number: | B6KFQ5 |
|---|
| Protein Name: | Vacuolar protein sorting-associated protein 35 |
|---|
| Length: | 852 |
|---|
| Molecular Weight: | 95636.00 |
|---|
| Species: | Toxoplasma gondii (strain ATCC 50861 / VEG) [432359] |
|---|
| Number of TMSs: | 2 |
|---|
| Substrate |
protein polypeptide chain |
|---|
1: MIMEHDQEKL LDEASAVVKE QARYMKRAID SDNLREALKH ASNMICELRT SLLSPKTYYE
61: LYMLVFHELQ HLSAFFSDKS RHNRKMSELY ESVQHAGNII PRLYLLITVG ASYIKSREAP
121: ACDILRDMTE LCKGVQHPMR GLFLRFYLTQ MCKDKLPDVG SEYEREGAGT MNDAFAFLLT
181: NFTEATRLWV RLQHQGSARE RQKREKERHD LRVLVGSTLV RMAQLDGMSV EFYREEALPR
241: LLEQVVGCRD GMAQQYLLDC IIQVFSDECH LQTLDPFLQA CLNVQPTVDL KAIFVNLLNR
301: LANFVQSEPE SVPADVDVFA LFRRYILELQ DRYLLSLSES SSSQSNGVKE GSLDSPPVAG
361: SLVGNLSGGK TPPSTDLTSL LELQMAFLSF TLTLFPDRVD HVDGILASTA VLLSRCLSEK
421: REDGGEARSG EQSRLSPAGV EAVVELLSSP LRTLSLSVLE IEHFPCLMGY LDFDTRKQVA
481: VSMVSAVLGS NVALDQPSAL SRFLEFISPL VLDAPDTPLD EDEGGASSAF SAEQQSVSKL
541: VHLLHNPDTD LHFALLCIAR EKFGEGGLRR LRYTLPPLVV AALQLVPRIL DRVEEHQRGD
601: SDLPAPTVSA KKIFQFVHGS CTQLVQCSAQ TALRLFLMSA IVADSANLRC PGSYEAITYE
661: YLTQALVCYE EEISDSKSQY NLISEFVGSV VGHIHTLEKD NYENISAKIT QHAAKLLKRP
721: DQCRAILTCS HLFWNNESVR DSRRVLECLQ KCLKIADIAV QSSTAHVCLF TDILDKYIYY
781: YERDNHEVTV DFIQNLLALC AEHVNFALQE AGQEEALASF RNTVRYLKRK KETEGAKWRG
841: LTGLNEISVS TS