3.A.3.1.15 Silkworm nerve Na+,K+-ATPase, α-subunit of 1009 aas and 10 TMSs (77% identical to the human ortholog). and the β-subunit of 326 aas and 1 TMS (30% identical to the human homolog). This ATPase, in contrast to mamalian ATPases, has high affinity for K+, but low affinity for Na+, suggesting that the β-subunit is responsible for the difference in Na+ affinity (Homareda et al. 2017).
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Accession Number: | BAS22117.1 |
Protein Name: | BAS22117.1 Na,K-ATPase alpha-subunit [Bombyx mori] |
Length: | 1010 |
Molecular Weight: | |
Species: | Bombyx mori [7091] |
Number of TMSs: | 8 |
Substrate |
sodium(1+), potassium(1+) |
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1: MGETSRKPPA KKRKPGDLED LKQELDIDYH KVTPEELYQR FQTHPENGLS HAKAKENLER
61: DGPNALTPPK QTPEWVKFCK NLFGGFALLL WIGAILCFIA YGIQASTVEE PADDNLYLGI
121: VLAAVVIVTG IFSYYQESKS SKIMESFKNM VPQFATVIRE GEKLTLRAED LVLGDIVEVK
181: FGDRIPADIR IIEARGFKVD NSSLTGESEP QSRGAEFTNE NPLETKNLAF FSTNAVEGTA
241: KGIVICCGDN TVMGRIAGLA SGLDTGETPI AKEIHHFIHL ITGVAVFLGV TFFVIAFILG
301: YHWLDAVIFL IGIIVANVPE GLLATVTVCL TLTAKRMASK NCLVKNLEAV ETLGSTSTIC
361: SDKTGTLTQN RMTVAHMWFD NQIIEADTTE DQSGVQYDRT SPGFKALAKI ASLCNRAEFK
421: GGQDGVPILK KEVAGDASEA ALLKCMELAL GDVLSIRKRN KKVCEIPFNS TNKYQVSIHE
481: SDDPSDPRHL LVMKGAPERI LERCSTIFIG GKEKVLDEEM KEAFNNAYLE LGGLGERVLG
541: FCDLQLPSDK YPIGYKFNTD DPNFPLDNLR FVGLMSMIDP PRAAVPDAVA KCRSAGIKVI
601: MVTGDHPITA KAIAKSVGII SEGNETVEDI AARLNIPVSE VNPREAKAAV VHGTELRELN
661: SDQLDEILKF HTEIVFARTS PQQKLIIVEG CQRLGAIVAV TGDGVNDSPA LKKADIGVAM
721: GIAGSDVSKQ AADMILLDDN FASIVTGVEE GRLIFDNLKK SIAYTLTSNI PEISPFLAFI
781: LCDIPLPLGT VTILCIDLGT DMVPAISLAY EAPESDIMKR QPRDPYRDNL VNRRLISMAY
841: GQIGMIQAAA GFFVYFVIMA ENGFLPMKLF GIRKQWDSKA INDLTDSYGQ EWTYRDRKAL
901: EFTCHTAFFV SIVVVQWADL IICKTRRNSI IHQGMRNWAL NFGLIFETAL AAFLSYTPGM
961: DKGLRMYPLK FVWWLPAIPF MLSIFIYDEI RRFYLRRNPG GWLEQETYY