3.A.1.147.6
Putative two component ABC exporter. There are 78 ABC systems including 28 importers and 50 exporters. Based on NBD sequence similarity, ABC transporters in C. difficile were classified into 12 sub-families according to their substrates (Pipatthana et al. 2021). All ABC exporters, accounting for 64% of the total ABC systems, may be involved in antibiotic resistance.
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| Accession Number: | C9XJW9 |
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| Protein Name: | Putative ABC transporter, permease protein |
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| Length: | 531 |
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| Molecular Weight: | 60103.00 |
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| Species: | Clostridium difficile (strain CD196) [645462] |
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| Number of TMSs: | 12 |
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| Substrate |
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1: MSNLSILIKT NIINEFKLNA LKKADSREKQ KIMGMILSVV IITGLLIFYV TSISLSLVDI
61: LKQINQMEML LIFGFGLSTL TTIVTSLYKT SSYLFQAKDL DLLTSLPIKE STVLASKILM
121: LVGANYLFSS ICMIIPAVVY FFNSDVSITY FPYLILLFLA LPLLPIVASS IIFMFIGQIS
181: SRIKYKNLIL IIGSIILMLL YTLLMTRLNS MSVEMLKNSV SISETIRKIY PPIYYFVDAL
241: KTGSVVSFLA FIAISIIPFF MFVTLFAKKF KDINAKMSEG YKSKTYKFKS QKTSRPSKAL
301: LKKEFKRYTS SFIYFLNSSA GLLFLIIGTI LILLFGADKV GELLKLNIDF NFIKIQLLGV
361: FFFIIVMNCT TYCSISLEGK NLWILKSSPI DEREIFWSKI LMNFLLNAPL SILCLILVSI
421: RLGFEIQFII VSICLIASFS MFVALMGLLS NLLYPNLDWK NEMAVVKRSA SMIITMLVSL
481: AYVIILGGIY VLLGISFLNI YIILASILTF ILDFMIWRII STKGVRIFKN L