9.A.34.1.1
The nuclear export protein complex, Brr6-Brl1-Apq12 (de Bruyn Kops and Guthrie 2001). Apq12 may be involved
in the regulation of lipid homeostasis in the endoplasmic reticulum,
thereby impacting nuclear pore complex biogenesis and localization, and
nucleocytoplasmic mRNA transport (Lone et al. 2015). Brr6 and the C-terminal 140 aas of Brl1 are homologous.
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| Accession Number: | P40532 |
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| Protein Name: | Nuclear membrane organization protein APQ12 |
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| Length: | 138 |
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| Molecular Weight: | 16508.00 |
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| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
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| Number of TMSs: | 3 |
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| Location1 / Topology2 / Orientation3: |
Nucleus membrane1 / Multi-pass membrane protein2 |
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| Substrate |
messenger RNA |
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1: MDATQPQYEL SVVTQCLKSA IDVIQWLIPT ITKFSQSHPL VFQLLFIFFT FYVFYKLLMN
61: FITLVKRFLY LTLVVTCIGI YMRGSQQFLT VDLLNFYNFV MSNRYYAFKI YTLFINALER
121: EINTVYHLAQ MKMEQLLK