3.A.1.103.10
Wzm (M; 280 aas; 6 or 7 TMSs in a 2 + 3 + 1 or 2 TMS arrangement)-Wzt (C) ABC lipid-linked galactan precursor exporter. Deletion of the encoding genes results in severe morphological changes and the accumulation of an aberrantly long galactan precursor. A model for coupled synthesis and export of the galactanpolymer precursor in mycobacteria has been proposed (Savková et al. 2021). The two encoding genes are separated by a gene that encodes a galactofuranosyltransferase, GlfT1.
|
| Accession Number: | P72047 |
|---|
| Protein Name: | Probable O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter RfbE |
|---|
| Length: | 273 |
|---|
| Molecular Weight: | 29992.00 |
|---|
| Species: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [83332] |
|---|
| Substrate |
|
|---|
1: MSDPHHPHIQ THNAWVEFPI FDAKSRSLKK AVLGKAGGTI GRNNSNVVVI EALRDITMEL
61: NLGDRVGLVG HNGAGKSTLL RLLSGIYEPT RGWAKVTGRV APVFDLGIGM DPEISGYENI
121: IIRGLFLGQT RKQMQAKVDE IAEFTELGEY LSMPLRTYST GMRVRLAMGV VTSIDPEILL
181: LDEGIGAVDA DFLRKAQSRL QNLVERSGIL VFASHSNEFL ARLCKTAIWI DHGVIRLAGG
241: IEEVVRAYEG EDAARHVREV LAETQADRQN VQG