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1.B.14.2.3
HpuAB hemoglobin-haptoglobin receptor; porphyrin transporter (HpuA=lipoprotein; HpuB=OMR porin).  Surface exposed loops in the gonococcal HpuB transporter are important for hemoglobin binding and utilization (Awate et al. 2023).

Accession Number:P96949
Protein Name:HpuB
Length:810
Molecular Weight:90627.00
Species:Neisseria meningitidis (serogroup C) [135720]
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Peripheral membrane protein2
Substrate

Cross database links:

Pfam: PF07715    PF00593   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0004872 F:receptor activity
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Molecular characterization of hpuAB, the haemoglobin-haptoglobin-utilization operon of Neisseria meningitidis.”  Lewis L.A.et.al.   9157245

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPIPFKPVLA VAAIAQAFPA FAADPAPQSA QTLNEITVTG THKTQKLGEE KIRRKTLDKL 
61:	LVNDEHDLVR YDPGISVVEG GRAGSNGFTI RGVDKDRVAI NVDGLAQAES RSSEAFQELF 
121:	GAYGNFNANR NTSEPENFSE VTITKGADSL KSGSGALGGA VNYQTKSASD YVSEDKPYHL 
181:	GIKGGSVGKN SQKFSSITAA GRLFGLDALL VYTRRFGKET KNRSTEGNVE IKNDGYVYNP 
241:	TDTGGPSKYL TYVATGVARS QPDPQEWVNK STLFKLGYNF NDQNRIGWIF EDSRTDRFTN 
301:	ELSNLWTGTT TSAATGDYRH RQDVSYRRRS GVEYKNELEH GPWDSLKLRY DKQRIDMNTW 
361:	TWDIPKNYDL RGINSEVYHS FRHIRQNTAQ WTADFEKQLD FSKAVWAAQY GLGGGRGDNA 
421:	NSDYSYFVKL YDPKILTSNQ AKITMLIENR SKYKFAYWNN VFHLGGNDRF RLNAGIRYDK 
481:	NSSSAKDDPK YTTAIRGQIP HLGSERAHAG FSYGTGFDWR FTKHLHLLAK YSTGFRAPTS 
541:	DETWLLFPHP DFYLKANPNL KAEKAKNWEL GLAGSGKAGN FKLSGFKTKY RDFIELTYMG 
601:	VSSDNPNKPT YAPLSDGTAL VSSPVWQNQN RSSAWVKGLE FNGTWNLDSI GLPQGTHAGV 
661:	NVSYIKGKAK QTNGQETPIN ALSPWSAVYN LGYDAPSKRW GINAYATRTA AKKPSDTVHS 
721:	NDDLNNPWPY AKHSKAYTLF DLSAYLNIGK QVTLRAAAYN ITNKQYYTWE SLRSIREFGT 
781:	VNRVDNKTHA GIQRFTSPGR SYNFTIEAKF