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|---|---|
| Accession Number: | Q07418 |
| Protein Name: | Pex19 aka Peroxin-19 |
| Length: | 342 |
| Molecular Weight: | 38706.00 |
| Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
| Location1 / Topology2 / Orientation3: | Cytoplasm1 / Lipid-anchor2 / Cytoplasmic side3 |
| Substrate | protein polypeptide chain |
Cross database links:
| DIP: | DIP-1563N |
|---|---|
| RefSeq: | NP_010218.2 |
| Entrez Gene ID: | 851494 |
| Pfam: | PF04614 |
| KEGG: | sce:YDL065C |
Gene Ontology
GO:0005829
C:cytosol
GO:0005789
C:endoplasmic reticulum membrane
GO:0005778
C:peroxisomal membrane
GO:0033328
F:peroxisome membrane targeting sequence binding
GO:0005515
F:protein binding
GO:0032527
P:protein exit from endoplasmic reticulum
GO:0045046
P:protein import into peroxisome membrane
GO:0050821
P:protein stabilization
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References (17)[1] “Pex19p, a farnesylated protein essential for peroxisome biogenesis.” Goette K.et.al. 9418908 [2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.” Jacq C.et.al. 9169867 [3] “Saccharomyces cerevisiae Pex3p and Pex19p are required for proper localization and stability of peroxisomal membrane proteins.” Hettema E.H.et.al. 10637226 [4] “Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome.” Eckert J.H.et.al. 12876220 [5] “Sequencing and comparison of yeast species to identify genes and regulatory elements.” Kellis M.et.al. 12748633 [6] “Global analysis of protein localization in budding yeast.” Huh W.-K.et.al. 14562095 [7] “Global analysis of protein expression in yeast.” Ghaemmaghami S.et.al. 14562106 [8] “Finding functional features in Saccharomyces genomes by phylogenetic footprinting.” Cliften P.F.et.al. 12775844 [9] “Peroxisomal membrane proteins contain common Pex19p-binding sites that are an integral part of their targeting signals.” Rottensteiner H.et.al. 15133130 [10] “Contribution of the endoplasmic reticulum to peroxisome formation.” Hoepfner D.et.al. 16009135 [11] “Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae.” Tam Y.Y.C.et.al. 16087670 [12] “Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells.” Vastiau I.M.K.et.al. 16791427 [13] “The dynamin-like protein Vps1p of the yeast Saccharomyces cerevisiae associates with peroxisomes in a Pex19p-dependent manner.” Vizeacoumar F.J.et.al. 16520372 [14] “Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals.” Vizeacoumar F.J.et.al. 16551610 [15] “Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery.” Girzalsky W.et.al. 16679311 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MNENEYDNFD DLDDLLDEDP TKLDEAEPDD VQAKGSVYND SENKEKNAES KDSDGVQVAN 61: ESEEDPELKE MMVDLQNEFA NLMKNNGNEN NVKTEDFNKL ISALEEAAKV PHQQMEQGCS 121: SLKSNSTDKG TVNGSNPGFK NIVSNTLDRL KENGNKVDTS LAEETKESQR SGQNNNIDDI 181: LSQLLDQMVA SGGKESAENQ FDLKDGEMDD AITKILDQMT SKEVLYEPMK EMRSEFGVWF 241: QENGENEEHK EKIGTYKRQF NIVDEIVNIY ELKDYDELKH KDRVTELLDE LEQLGDSPIR 301: SANSPLKHGN EEEELMKMLE IDGNDPNLGN LDKELTDGCK QQ