3.A.1.25.1 The biotin uptake porter (binding receptor lacking) (see also the VUT or ECF family; BioY; 2.A.88.1.1) (Rodionov et al., 2006; Hebbeln et al., 2007). BioN (the EcfT component of the biotin transporter) appears to be required for intramolecular signaling and subunit assembly (Neubauer et al., 2009). The Ala-Arg-Ser and Ala-Arg-Gly signatures in BioN are coupling sites to the BioM ATPases (Neubauer et al., 2011). Subunit stoicheometries have been estimated with the prediction that there are oligomeric forms of BioM and BioY in the BioMNY complex (Finkenwirth et al. 2010).
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Accession Number: | Q6GUB1 |
Protein Name: | Permease protein BioN |
Length: | 202 |
Molecular Weight: | 21997.00 |
Species: | Rhizobium etli [29449] |
Number of TMSs: | 4 |
Substrate |
biotin |
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Pfam: |
PF02361
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GO:0015087
F:cobalt ion transmembrane transporter activity
GO:0009236
P:cobalamin biosynthetic process
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[1] “The Rhizobium etli bioMNY operon is involved in biotin transport.” Guillen-Navarro K. et.al. 16099603
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1: MQSLYVEGNS RMHRLSPRAK LLSLTAFAIL LFISHNLLLL SGAVLVAAVL YGTVGLPIGE
61: ALLRLRPIFL TIAVVALFNL IFNPWQAALV PVLRLTALML LAASVTATTT ITEFIDEVTA
121: LARPLERTGR VQADDIGLAL GLVLRFVPEI VNRYQAIREA HKARGLKVRP TSLLAPLIIL
181: TLKDADNVAA AIDARRIRRH GS