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3.A.7.8.1
Competence system for DNA uptake (ComB) (Hofreuter et al., 2003; Karnholz et al., 2006). DNA uptake into the periplasm occurs preferentially at the poles. Transport into the cytoplasm depends on ComEC. Thus, DNA uptake may occur in a two step process (Stingl et al., 2010).

Accession Number:Q8RMY6
Protein Name:VirB10 aka ComB10
Length:402
Molecular Weight:45049.00
Species:Helicobacter pylori (Campylobacter pylori)   [210]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate DNA

Cross database links:

Pfam: PF03743   

References (1)

[1] “Cluster of type IV secretion genes in Helicobacter pylori's plasticity zone.”  Kersulyte D.et.al.   12813069

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKQSLLKKIG LGVGGFVVLM ALGLLTNKGS NNNNKEEIFQ VSESKFPLSD YFFEEVKEEP 
61:	KEKAKETPEV TTQEPTTQTS PNPSVSANPN IKDYSHLNNN LNQQNNTITH LQQVLQSPSK 
121:	IKPKPKHTKE QLEFLNTRLK PLEPTKPATK PEMEYGVDSF TNLKYKDIGT NEHKLLRTIT 
181:	ADRMIPAFLI TPISSQIAGK VTAQVESDIF ASMGRAVLIP KGSKVIGYYN NNNQIGQYRL 
241:	NIAWTRIITP QGINIMLTNA RGADVKGYNG LVGKYISRNF QRYGIPLLTN TLSNGLLIGI 
301:	TSALANRQNR KGDGNPFFGD YLLMQLTRNT GMGINQVINQ MLRQYGAQNP IIIIREGSRV 
361:	FISPNLDIFI PKPKDGEVLA EFFKEKKPPI KTKEEINNEE EI