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2.A.6.2.25 The gold (Au²⁺) resistance efflux pump, GesABC (induced by GolS in the presence of Au²⁺; also mediates drug resistance when induced by Au²⁺ (Pontel et al., 2007). Also exports a variety of organic chemicals including chloramphenicol (Conroy et al., 2010).
Accession Number:	Q8ZRG9
Protein Name:	GesB
Length:	1055
Molecular Weight:	113914.00
Species:	Salmonella typhimurium [90371]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Cell outer membrane¹ / Multi-pass membrane protein²
Substrate	chloramphenicol, drug

RefSeq:	NP_459346.1
Entrez Gene ID:	1251870
Pfam:	PF00873
BioCyc:	STYP99287:STM0351-MONOMER
KEGG:	stm:STM0351
Gene Ontology GO:0016021 C:integral to membrane GO:0005215 F:transporter activity GO:0006810 P:transport
References (1) [1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.” McClelland M.et.al. 11677609

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKFTHFFIAR PIFAIVLSLL MLLAGAIAFL KLPLSEYPAV TPPTVQVSAS YPGANPQVIA 
61:	DTVAAPLEQV INGVDGMLYM NTQMAIDGRM VISIAFEQGT DPDMAQIQVQ NRVSRALPRL 
121:	PEEVQRIGVV TEKTSPDMLM VVHLVSPQKR YDSLYLSNFA IRQVRDELAR LPGVGDVLVW 
181:	GAGEYAMRVW LDPAKIANRG LTASDIVTAL REQNVQVAAG SVGQQPEASA AFQMTVNTLG 
241:	RLTSEEQFGE IVVKIGADGE VTRLRDVARV TLGADAYTLR SLLNGEAAPA LQIIQSPGAN 
301:	AIDVSNAIRG KMDELQQNFP QDIEYRIAYD PTVFVRASLQ SVAITLLEAL VLVVLVVVMF 
361:	LQTWRASIIP LVAVPVSLVG TFALMHLFGF SLNTLSLFGL VLSIGIVVDD AIVVVENVER 
421:	HISQGKSPGE AAKKAMDEVT GPILSITSVL TAVFIPSAFL AGLQGEFYRQ FALTIAISTI 
481:	LSAINSLTLS PALAAILLRP HHDTAKADWL TRLMGTVTGG FFHRFNRFFD SASNRYVSAV 
541:	RRAVRGSVIV MVLYAGFVGL TWLGFHQVPN GFVPAQDKYY LVGIAQLPSG ASLDRTEAVV 
601:	KQMSAIALAE PGVESVVVFP GLSVNGPVNV PNSALMFAML KPFDEREDPS LSANAIAGKL 
661:	MHKFSHIPDG FIGIFPPPPV PGLGATGGFK LQIEDRAELG FEAMTKVQSE IMSKAMQTPE 
721:	LANMLASFQT NAPQLQVDID RVKAKSMGVS LTDIFETLQI NLGSLYVNDF NRFGRAWRVM 
781:	AQADAPFRMQ QEDIGLLKVR NAKGEMIPLS AFVTIMRQSG PDRIIHYNGF PSVDISGGPA 
841:	PGFSSGQATD AIEKIVRETL PEGMVFEWTD LVYQEKQAGN SALAIFALAV LLAFLILAAQ 
901:	YNSWSLPFAV LLIAPMSLLS AIVGVWVSGG DNNIFTQIGF VVLVGLAAKN AILIVEFARA 
961:	KEHDGADPLT AVLEASRLRL RPILMTSFAF IAGVVPLVLA TGAGAEMRHA MGIAVFAGML 
1021:	GVTLFGLLLT PVFYVVVRRM ALKRENRVDS HDQQA

2.A.6.2.25
The gold (Au²⁺) resistance efflux pump, GesABC (induced by GolS in the presence of Au²⁺; also mediates drug resistance when induced by Au²⁺ (Pontel et al., 2007). Also exports a variety of organic chemicals including chloramphenicol (Conroy et al., 2010).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.6.2.25The gold (Au2+) resistance efflux pump, GesABC (induced by GolS in the presence of Au2+; also mediates drug resistance when induced by Au2+ (Pontel et al., 2007). Also exports a variety of organic chemicals including chloramphenicol (Conroy et al., 2010).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.6.2.25
The gold (Au²⁺) resistance efflux pump, GesABC (induced by GolS in the presence of Au²⁺; also mediates drug resistance when induced by Au²⁺ (Pontel et al., 2007). Also exports a variety of organic chemicals including chloramphenicol (Conroy et al., 2010).