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2.A.6.2.25 The gold (Au²⁺) resistance efflux pump, GesABC (induced by GolS in the presence of Au²⁺; also mediates drug resistance when induced by Au²⁺ (Pontel et al., 2007). Also exports a variety of organic chemicals including chloramphenicol (Conroy et al., 2010).
Accession Number:	Q8ZRH0
Protein Name:	GesC
Length:	503
Molecular Weight:	55410.00
Species:	Salmonella typhimurium [90371]
Number of TMSs:	2
Location¹ / Topology² / Orientation³:	Cell outer membrane¹ / Multi-pass membrane protein²
Substrate	chloramphenicol, drug

Pfam:	PF02321
BioCyc:	STYP99287:STM0350-MONOMER
Gene Ontology GO:0016020 C:membrane GO:0008289 F:lipid binding GO:0005215 F:transporter activity GO:0006810 P:transport
References (1) [1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.” McClelland M.et.al. 11677609

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MRTALIRMIS KHNDGNGIMK ITFTGYRQTA TLATLAFVTT LAGCTMAPKH ERPASPTAMV 
61:	YPYATSTVSG APDAADIGWR DFFHDPLLQE LIAIALRNNR DLRKAGLNVE AARALYRIQR 
121:	AEMLPTLGIA TAMDASRTPA DLSVMDESEI NRRYEAAGAT TAWELDLWGR VRSLSDQALA 
181:	AYMALDETYI AARMSLVSEV ASAWLTLRAD RELLRLTEDT LAAQKSSYTL TTQLARTGNA 
241:	TQLDLRMAEI ALRSAEINRA AYTRQLARDR NALELLLGQP LTPELSRRLN EAVTLTEGAI 
301:	PTTLPGGLPS DLLVRRPDIR AAEYRLRGAN ARIGAARAAF FPTISLTGSA GTASASLSGL 
361:	FEPGSGSWRF LPQITLPLFH GGALRADLDR AHVQKQIEIA RYENVIQQAF RDVADGLAGQ 
421:	RTLNDQVQSE QRAVEASQIA YELAGLRFQE GVDDYLTLLD THRMLYGAQQ RLVRTRLMQQ 
481:	LNIINLYKAL GGGWREYSEK KQG

2.A.6.2.25
The gold (Au²⁺) resistance efflux pump, GesABC (induced by GolS in the presence of Au²⁺; also mediates drug resistance when induced by Au²⁺ (Pontel et al., 2007). Also exports a variety of organic chemicals including chloramphenicol (Conroy et al., 2010).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.6.2.25The gold (Au2+) resistance efflux pump, GesABC (induced by GolS in the presence of Au2+; also mediates drug resistance when induced by Au2+ (Pontel et al., 2007). Also exports a variety of organic chemicals including chloramphenicol (Conroy et al., 2010).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.6.2.25
The gold (Au²⁺) resistance efflux pump, GesABC (induced by GolS in the presence of Au²⁺; also mediates drug resistance when induced by Au²⁺ (Pontel et al., 2007). Also exports a variety of organic chemicals including chloramphenicol (Conroy et al., 2010).