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2.A.6.2.11 Solvent and antibiotic efflux pump, TtgGHI (SrpABC) (Kieboom et al. 1998; Terán et al., 2007) (solvents extruded include toluene, styrene, m-xylene, ethylbenzene and propylbenzene) (Teran et al., 2007). TtgGHI is the same as SrpABC (Kieboom et al., 1998)
Accession Number:	Q93PU3
Protein Name:	TtgI
Length:	470
Molecular Weight:	51429.00
Species:	Pseudomonas putida [303]
Location¹ / Topology² / Orientation³:	Cell outer membrane¹ / Lipid-anchor²
Substrate	styrene, m-xylene, toluene, ethylbenzene, propylbenzene

Pfam:	PF02321
Gene Ontology GO:0009279 C:cell outer membrane GO:0005886 C:plasma membrane GO:0008289 F:lipid binding GO:0005215 F:transporter activity GO:0006810 P:transport
References (2) [1] “Three efflux pumps are required to provide efficient tolerance to toluene in Pseudomonas putida DOT-T1E.” Rojas A.et.al. 11395460 [2] “In vivo and in vitro evidence that TtgV is the specific regulator of the TtgGHI multidrug and solvent efflux pump of Pseudomonas putida.” Rojas A.et.al. 12896994

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKFKSLPMFA LLMLGGCSLI PDYQQPAAPM QAQWPTGQAY GGQGDQRSIA TALPKAKEFF 
61:	KDPALVRLLD AALENNRDLR IAAKNVESYR ALYRIQRAER FPTLDGQASG NRTRLPDDLS 
121:	PTGDSRIDSQ YQVGLVTAYE LDLFGRIRSL SNQALEKYLA TEEAQRSVQI ALIGDVATTY 
181:	FLWRTDQALL ELTEATLTSY VESLAMIESS AWAGTSSELD VRQARTLVNQ AQAQQALYTR 
241:	RIAQDVNALE LLLGSKIPTD LPKNSPLAMS ALGKVPAGLP ADLLLNRPRI RSAEHQLMAA 
301:	NANIGAARAA FFPRISLTAS AGSASSDLDG LFNSGSDSWS FAPQISVPIF NAGKLRANLD 
361:	YAELQKDVGV ATYEKSIETA FREVADGLAA RGTYGKQLSA QSELVDNYKA YFSLAQQRYD 
421:	QGVDSYLTVL DAQRELFSSQ QKLLNDQLDQ INSEVQLYKA LGGGWSVSQN

2.A.6.2.11
Solvent and antibiotic efflux pump, TtgGHI (SrpABC) (Kieboom et al. 1998; Terán et al., 2007) (solvents extruded include toluene, styrene, m-xylene, ethylbenzene and propylbenzene) (Teran et al., 2007). TtgGHI is the same as SrpABC (Kieboom et al., 1998)

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.6.2.11Solvent and antibiotic efflux pump, TtgGHI (SrpABC) (Kieboom et al. 1998; Terán et al., 2007) (solvents extruded include toluene, styrene, m-xylene, ethylbenzene and propylbenzene) (Teran et al., 2007). TtgGHI is the same as SrpABC (Kieboom et al., 1998)

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.6.2.11
Solvent and antibiotic efflux pump, TtgGHI (SrpABC) (Kieboom et al. 1998; Terán et al., 2007) (solvents extruded include toluene, styrene, m-xylene, ethylbenzene and propylbenzene) (Teran et al., 2007). TtgGHI is the same as SrpABC (Kieboom et al., 1998)