3.A.1.1.42
α-glucoside uptake permease, Agl3E/Agl3F/Agl3G. Plays a role in normal morphogenesis and antibiotic production. Strongly induced by trehalose and melibiose, and weakly induced by lactose and glycerol but not glucose (Hillerich and Westpheling 2006).The operon is controlled by a GntR homologue, Agl3R, and downstream of the gntR gene is a gene encoding an extracellular carbohydrase.
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| Accession Number: | Q9FBS7 |
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| Protein Name: | Putative sugar-binding integral membrane transport protein |
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| Length: | 303 |
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| Molecular Weight: | 32949.00 |
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| Species: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226] |
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| Number of TMSs: | 7 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
alpha-glucoside |
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1: MAPATAPNRR PRRPAPAPRT RRRASGTVAG TSLWRLPLLL VSASFMVIPL WLLVVNAFKS
61: EQDIRDSPFG LPLTRLSLRP LRDAFANPDF DVVRAYGITL LFVLLVNVLS LLVSAPVSYV
121: IARGTTRWHT ALLLLFVAGT FVPSQVLLIP VVYVLKYLGL MGTVPGFVLF ETALTLPVSV
181: FLYSAYIRTI PRELDQAASV DGLGRLRTFQ LVVLPLMRPM VATAVILHSL SVWNDFANPQ
241: IILGPGSGLY TVTTGVYAAV GKYSTHYAVV FPNLLLAVAP ALAFFAIMQR HIISGLTSGA
301: LKG