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2.A.6.2.30
VexEF-TolC mediates resistance to various antimicrobials; ethidium efflux is Na+-dependent (Rahman et al., 2007)

Accession Number:Q9K2Y1
Protein Name:TolC
Length:438
Molecular Weight:47751.00
Species:Vibrio cholerae [666]
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Peripheral membrane protein2
Substrate ethidium, drug

Cross database links:

RefSeq: NP_232066.1   
Entrez Gene ID: 2612978   
Pfam: PF02321   
KEGG: vch:VC2436   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0015031 P:protein transport

References (1)

[1] “DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.”  Heidelberg J.F.et.al.   10952301

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKLLPLFVS AALGTLSSAV WAENLAEIYN QAKENDPQLL SVAAQRDAAF EAVTSSRSAL 
61:	LPQINLTAGY NINRSDQAPR ESDLLSAGIN FSQELYQRSS WVSLDTAEKK ARQADSQYAA 
121:	TQQGLILRVA KAYFEVLRAQ DNLEFVRAEK AAVGRQLEQT KQRFEVGLSA ITDVHDAQAQ 
181:	FDGVLADEVL AENSLTNSYE ALREITGQEY SKLAVLDTKR FAASRTTESS EALIEKAQQQ 
241:	NLSLLAARIS QDVARDNISL ASSGHLPSLT LDGGYNYGNN SNDNAKNTSG EEYNDFKIGV 
301:	NLKVPLYTGG NTTSLTKQAE FAYVAASQDL EAAYRSVVKD VRAYNNNINA SIGALRAYEQ 
361:	AVISAKSALE ATEAGFDVGT RTIVDVLDAT RRLYDANKNL SNARYDYILS VLQLRQAIGT 
421:	LSEQDVMDVN AGLKVAKK