2.A.80.1.2
Terephthalate (TPA) aromatic acid uptake transport system, TpiBA/TphC (Hosaka et al. 2013). May transport several aromatic acids including isophthalate, o-phthalate and protocatechuate. Consists of three subunits: TpiB (503 aas and 13 TMSs), TpiA (162 aas and 4-5 TMSs) and TphC (322 aas and 1 TMS. tpiAB comprise an operon while tphC maps elsewhere. o-phthalate and protocatecuate may use other receptors (Hosaka et al. 2013).
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| Accession Number: | S6BBY9 |
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| Protein Name: | Large transmembrane protein of the aromatic acids transporter |
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| Length: | 503 |
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| Molecular Weight: | 53004.00 |
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| Species: | Comamonas sp. E6 [364029] |
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| Number of TMSs: | 13 |
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| Substrate |
(3,4-dihydroxyphenyl)acetate, isophthalate(2-), terephthalate(2-), dibutyl phthalate |
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1: MDLIQNLSTG FGVAFTFQNL IYCFVGCLLG TLIGVLPGIG PVATIAMLLP ATYALPPVAA
61: LIMLAGIYYG AQYGGSTTAI LVNLPGESSS VVTVIDGYQM ARKGRAGPAL AAAGIGSFFA
121: GCVGTVILAA FAPPLTEVAF KFGPAEYFSL MTLGLIGAVV LASGSLLKAI AMIVLGLLLG
181: MVGTDVNSGV ARYSFDIPEL TDGIDFVVIA MGVFGYGEII ANLSKPDDER EVFAAKVTGL
241: LPTSEDFKRM LPAMLRGTAL GSALGILPGG GAMLSAFAAY TIEKKTKLKP GEVPFGQGNI
301: RGVCAPESAN NAGSQTSFIP LLTLGIPPNA VMALMVGAMT IHNIQPGPQV MTSNPELFWG
361: LIASMWIGNL MLIILNLPLI GVWIKLLTVP YRWLFPSIVL FCAIGVYGTN NNVWDVWMVG
421: IFGFIGYVFH KLGTEPAPLL LGFILGPMME ENLRRALLLS RGDWSVFVTR PISACLLAAA
481: VVLLVIVLMP AVKNKREEAF VED