4.A.3.2.14
PTS transporter, IICAB2^cel.  IIC has 487 aas and 10 predicted TMSs.  This system transports cellobiose, cellotriose, and cellotetraose, and possible higher MW oligosaccharides in this series. It has its own IIB protein but uses the IIA protein of the Cel1 system (TC# 4.A.3.2.13) (Combret et al. 2025).  In addition to IIC, IIA and IIB, three additional proteins seem to be required for function, although what these biochemical functions are is not known.  These proteins are designated CelG (73 aas), CelH (67 aas) and CelI (137 aas) and are the last three proteins included in this system in TCDB (see Combret et al. 2025 for more details). UniProt acc #s for CelB2, CelC2, CelG, CelH and CelI of E. faecalis are Q836U5, Q836U4, Q836U3, Q836U2, and Q836U1, respectively.