| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
4.A.3.1.1 | Lactose (Lac) porter, LacEF (Kowolik and Hengstenberg 1998). This system is 87% identical to the LacEF ortholog in Streptococcus mutans (Rosey and Stewart 1992). | Bacteria |
Bacillota | Lactose (Lac) IICB-IIA complex of Staphylococcus aureus IIA (LacF) (P02909) IIBC (LacE) (P11162) |
|
4.A.3.1.2 | Bacteria |
Bacillota | ||
|
4.A.3.1.3 | Lactose PTS group translocator #2, IIA/IICB (Francl et al. 2012). | Bacteria |
Bacillota | Lactose PTS porter #2 of Lactobacillus gasseri |
|
4.A.3.2.1 | N,N'-diacetylchitobiose (Chb) porter (also transports cellobiose; Kachroo et al., 2007). | Bacteria |
Pseudomonadota | N,N'-diacetylchitobiose (Chb) IIC-IIB-IIA complex of E. coli IIA (ChbA), spP17335 IIB (ChbB), spP17409 IIC (ChbC), spP17334 |
|
4.A.3.2.2 | Lichenan oligosaccharide (Lic) porter | Bacteria |
Bacillota | Lichenan oligosaccharide (Lic) IIC-IIB-IIA complex of Bacillus subtilis IIA (LicA), spP46319 IIB (LicB), spP46318 IIC (LicC), spP46317 |
|
4.A.3.2.3 | N,N'-diacetylchitobiose porter, ChbABC | Bacteria |
Spirochaetota | N,N'diacetylchitobiose (Chb) IIC-IIB-IIA complex of Borrelia burgdorferi IIA (ChbA), AAC66323 IIB (ChbB), AAC66322 IIC (ChbC), AAC66324 |
|
4.A.3.2.4 | The cellobiose-specific (PtcA-PtcB-CelB) porter (Kowalczyk et al., 2008 ). | Bacteria |
Bacillota | PtcA-PtcB-CelB of Lactococcus lactis: CelB (C)(Q9CJ32) PtcB (B)(Q9CIF0) PtcA (A)(Q9CIE9) |
|
4.A.3.2.5 | The N,N' -diacetylchitobiose Enzyme II (Toratani et al., 2008) (>80% identical to the E. coli enzyme (4.A.3.2.1)). The IIA protein is the Serratia glucose IIA which is nearly identical to the E. coli IIAGlc (Crr). | Bacteria |
Pseudomonadota | The N,N' -diacetylchitobiose Enzyme II of Serratia marcescens IIA (ChbA) - Q8L3C4 IIB (ChbB) - Q8L3C3 IIC (ChbC) - Q8L3C2 |
|
4.A.3.2.6 | Glucosamine β(1→4) glucosamine (GlcN)2 (glucosamine dimer) transporter, VC1281-1283 (IIB; IIC; IIA, respectively) (Meibom et al., 2004) | Bacteria |
Pseudomonadota | (GlcN)2 transporter of Vibrio cholerae (IIA-IIB-IIC) IIB (Q9KSH5) IIA (Q9KSH3) IIC (Q9KSH4) |
|
4.A.3.2.7 | N,N'-diacetylchitobiose (cellobiose) PTS permease, CelABC (IIABC). Essential for normal virulence and biofilm formation by K. pneumoniae which causes pyogenic liver abscesses (Wu et al. 2012). 88% identical to the diacetylchitobiose II (4.A.3.2.1) of E. coli. These two proteins are probably orthologous. | Bacteria |
Pseudomonadota | CelABC of Klebsiella pneumoniae |
|
4.A.3.2.8 | N-, N'-diacetylchitobiose PTS permease, IIABCChb (Also called IIABCCel for cellbiose). The crystal structure of the 10 TMS IIC membrane component has been determined by x-ray crystallography (Cao et al. 2011). | Bacteria |
Bacillota | ChbIIABC of Bacillus cereus ChbA (CelA); IIB (100 aas) (Q72XP9) ChbB (CelB); IIC (433 aas) (Q72XQ0) ChbC (CelC); IIA (106 aas) (Q72XQ1) |
|
4.A.3.2.9 | PTS-type lactose transporter, IIC-IIB-IIA (Imai and Hall 1981; Hall et al. 1982). | Bacteria |
Pseudomonadota | Lactose permease of Klebsiella pneumoniae |
|
4.A.3.2.10 | Oligo β-(gluco)mannoside (derived from (gluco)mannan))-specific PTS transporter, GmuABC (YdhNMO). The glucomannan utilization operon (gmuBACDREFG, formerly ydhMNOPQRST) of Bacillus subtilis has been characterized (Sadaie et al. 2008). Transcription of the operon is induced by konjac glucomannan and requires the last mannanase gene (gmuG). Cellobiose and mannobiose, possible degradation products of glucomannan by GmuG, are strong inducers of transcription. An internal regulatory gene (gmuR) encodes a repressor of the operon, as disruption of this gene enhances transcription of the operon in the absence of inducers. The expression of the glucomannan utilizing operon is thus induced by degraded glucomannan products, and repressed by an internal repressor (Sadaie et al. 2008). | Bacteria |
Bacillota | GmuABC of Bacillus subtilis GmuA, IIA, 110 aas, O05506 GmuB, IIB, 103 aas, O05505 GmuC, IIC, 422 aas and 10 TMSs, O05507 |
|
4.A.3.2.11 | Cellobiose PTS transporter with one IIC protein, CelC1, of 435 aas and 10 predicted TMSs(Q8Y3Z4, and two sets of IIAB proteins, CelA1 (100 aas; Q927F6) and CelB1 (101 aas; Q8Y3Z5) as well as CelA2 (100 aas; Q92AT9) and CelB2 (102 aas; Q8Y6G7). Another IIC-like protein was also found (454 aas; 10 TMSs; Q8Y3X1) but it did not phosphorlyate cellobiose, and its function was not identified. Transcription of these genes is regulated by CelR (Cao et al. 2019). | Bacteria |
Bacillota | CelA1/A2/B1/B2/C1 of Listeria monocytogenes |