1.A.1.2.32
Potassium voltage-gated channel subfamily G member 4 of 535 aas and 6 TMSs + P-loop between TMSs 5 and 6, where the entire channel domain is between residues 220 - 460. The voltage gated (Kv) slow-inactivating delayed rectifier channel
regulates the development of hollow organs of the zebrafish. The
functional channel consists of the tetramer of electrically active Kcnb1
(Kv2.1) subunits and Kcng4b (Kv6.4) modulatory or electrically silent
subunits (Jędrychowska et al. 2024). This channel is found in fish but not mammals.
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| Accession Number: | XP_009301775.1 |
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| Protein Name: | XP_009301775.1 potassium voltage-gated channel subfamily G member 4 [Danio rerio] |
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| Length: | 536 |
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| Molecular Weight: | |
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| Species: | Danio rerio [7955] |
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| Number of TMSs: | 7 |
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| Substrate |
potassium(1+) |
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1: MPIISNANHD FSNLSVSTDD SSLDLFFTEI PETETIKGVY FQRAQRLCGI STLKDVDHSK
61: LALINVGGDR YTFPWSTLDE FPLSRLGQLR HCSSPDDIAQ LCDDYDEARR EFFFDRSSVA
121: FRVILNFLAA GKLRLLRQVC AVSLSDELTY WGIDPVHMER CCRRKLLSRV EDVAEKKKKE
181: DERKQKRHAL QRPLAQDKGF IRLMNRLQEI VENPHSGWAG KLFACFSVVM IAVTVISLCI
241: STLPDHENRG ECTEKCRNIF IVETVCVAWF SMEFLLRFLQ AESKMQFLRN PLNVIDVIAI
301: LPYYISLVVD SEDTSDEAEL NGAGTSRGYL DKLGLILRVM RALRILYVMR LARHSLGLQT
361: LGLTMQRSMR EFGLLLLFLC VAVALFSPLV HLAEKEFSKG KATGPNSFSS IPASYWWAII
421: SMTTVGYGDM VPYSIPGQVV AFSSILSGIL IMAFPATSIF HVFSRSYHEL KREQEMIYKE
481: ERVAILDATA KEDAQRLLKR DSFSWAIANR NSLRKDNGTA AIQPTLTAAA CCKDI