1.A.1.26.2
Voltage-gated potassium channel, KCh1, of 1966 aas with 12 TMSs in a 2 (residues 50 - 100) + 10 (residues 550 - 900) TMS arrangement (Wunderlich 2022).
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| Accession Number: | Q8I5E6 |
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| Protein Name: | Potassium channel K1 |
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| Length: | 1966 |
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| Molecular Weight: | 232187.00 |
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| Species: | Plasmodium falciparum (isolate 3D7) [36329] |
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| Number of TMSs: | 10 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
potassium(1+) |
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1: MNNDNIGREP IDVVYDKRFS SRIKPKTKKK KRNENRMRLV RIQHYIYNIF TSFLCLFIVI
61: LILYASIDIS INYGPVIILY ILILELGSML ISYILLQFPF FYRKLKNTFM RARNINKYSH
121: QYRPLYYDNN SFTDENESFN ISDDEKKEKR KRKHTYSFMS SDGGRKRSNF RRFLSSYKSK
181: KGNEFVNSKT MKNKTKKNTR RKGFLSFNWI GYKNGETNKN RNDNIVNDVY KKYNDDNKYN
241: DDNKYNDDNY NDDDNKYNDD DILNSHSEQD QRKKKKKKKE KRIVVFPRND TGGNSFKRES
301: IYIDDCNMWM KKTMRKSNRP NFKLTRSLSF NINMNKDDDL MMKDSASLDN IQIFLGHRSS
361: KFLREKNKLQ KRKTSIYNKY VPLTFASSYK DDFFKEILKS QTDGIISSSS DYSSSSEDSN
421: KNVYKTIYIN NNNNNVDKKG KIDEEDNIVV RNNIHSNENI IIKENPYSLR NAILFHKEKR
481: KYRKNINTLS DDDNKNFAFH SGKKKIKRKE KKRRCFIKLK CFNKIKNLYR FFINYNMKSS
541: KSSNNLYLFF RGFYIYTKHR FVHYLSYEPI WIVAILIRIV LWCIVWIWAA SYMERKPKNF
601: EITEWNMKNV PSFYGYIECT FQWCGVFDYF FGLYFSNNKL KYIFSFFSLI DFITTPVSSL
661: IMNFFVQDNI NHNYWFLILG PLRFLRLVRA ESTISSCFFW LNDVKIIIIG IIILALAILF
721: TFSGIMYILE APDIERDFVK PLDFVYFGVI TMSTVGYGDY TPVTKAGKFL TMFIIITCIS
781: FVAAQFKRLK EAMFSPKTVM GIIPKQDDDY ILILGPVSPT QLLYICKGIN NSFPNSVESI
841: FLFTPLPVVI YRYVYGSIVK NTNIKICISG GNECFICPSI IYDAVINSRA LYILNNVDSE
901: KYTLMYQQIF LASNNINFNN HDHQNQRISS DDILHNNIIN KYSKDKTKNW KYSDLFSEYK
961: NEINKNNMLN LEMNININNS YSIKEKDDQE CLLRFIGTYN ICNSLIPITL QLSNNTYEEL
1021: IKSMNVYNYI SIEELKYALL AKSVNCKGLF FLIINFFYKP KAVKSLKKYI IDLKLLMYNG
1081: MLRRKNRERL SSSNLKIKQP SQQKSRKGNL INKISLFFKK GQNHQLDAEG ISHDEKNNSN
1141: TSRTRGNNRN DHMDPQIKGK GVFEMNQKEQ KQVMLKEGMN KNMNKNIIKD MEKNMNSNGK
1201: DNINDSINES IEKNDLFFLN SLDPNDDRNI HNLSYKNYYY MLEKVNLNMY YYLEGLKYNI
1261: YRFQFPECMR GFLFQTASEY LYQKYSAFLI GIITINKEIF LNPVNYIIGE ENKYFYTSAF
1321: SGIILTTSLD SLIKLSSINN ISKKVYEYNK RLIEEKYKST FSKSWINSDD DHHNSDHKNF
1381: VTNTQIKETQ IDGDEVKIVL TSHDDSLHPS DRSVKNRKNS MKSIYNQKKS NLGDQKKKNR
1441: NQDDRTEHQV DDNNDSDYLQ IESVPKKKRN MYYSLVLGIC ELENYISAYK DAFVDKDKPL
1501: LLVCGWPDNI HMFFKYLKRN VYNSSYRNKN NSNIHTYDNN NNNNNNNNIY SKTVKNKKGK
1561: RKKMKKLNDD IKYNIIILSL HVPKFNYEND LFNYSENVVF IRGSPLNSYN LIQAGVFYAK
1621: RIIILNSNHS LFIDKDAYRI DNEVIIIKNI VNQLFNYISK NKENYFNLLR KTFPKEYIDI
1681: TINERIFLND NINNSPNINE MIKGKMSDSS YDSLDDNYSS DDDSSSSNYD DDDEDNDNDE
1741: DNVDNNNDHG GESLLLKKKR KKKNMIKLKK RALNVNNIFN INKNPYLICL IKNSESLEYI
1801: DGSINLSYEN YNDNEKMNKI WENCGEYIYT FELVSANIFV HEMLHNLVSF SLPISKYAIE
1861: YSVIYSLIGI DINEYSKNAQ KFHKNLNLST GYVNLVPIPS YFYKKSFYKC FSYFLHNKLS
1921: LCIGILRYID ISSLSNKSKK IFVLSCPSRT MKIEPHDQAY VIAHRM