1.A.1.26.4
K+ channel (K2 gene) of 1461 aas and 8 TMSs with 2 N-terminal TMSs (residues 1 - 80) followed by 6 TMSs (residues 180 - 360). The remainder of the protein is hydrophilic (Desai 2024).
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| Accession Number: | Q8IKI3 |
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| Protein Name: | Potassium channel K2 |
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| Length: | 1461 |
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| Molecular Weight: | 174221.00 |
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| Species: | Plasmodium falciparum (isolate 3D7) [36329] |
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| Number of TMSs: | 9 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
potassium(1+) |
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1: MKSGLFSMND IFFLVNSIFK YFLILLNGSH LLKLLYSSKE NIHIIEGLLC IITGVILKLS
61: LIYIYCTYFM NIYIIKDYRR KNVLNIFNMN NNYKRNGNVI ESDDFEYRKL IKKFFFKKVY
121: YSIKKKHKRI ELYMLKIYNS NFNYYFCNIR DMCYTIIWYI SLYYWRRDTY NMIWGFNKIP
181: TYIYNMLLIL LSTSYIDLVM VIISYNKSKY YLMKSKLLID IFFSAPCTYL FSKFIFVFEH
241: QIDIYFMMGF LRNIKIFLNV SYVRIEHNSI LTNTEIKIIR IVLGVLLLCN AFASTIYTIQ
301: AIHPYNLDNE NFNYFLNSYL DYFYFSIISI STVGYGDIFP INKLSKVVCI IFIFWTFIWV
361: PIQFNDLIIS IFSKKKTYGK ISMNNQKFIL LIGDVEPQQL NVFLFESVAQ GNKLKFHLLT
421: TYPINIYDEQ IKIADHFCIS LYIKNFDLNE KENINLLYSI NAQNAYYLFL FSNKFHNGHY
481: NIDTKSFTRL LILKKFLHGK KNAVIELRSN CVSNIVRSIG CENFIIVNLK HSLIVKNIKY
541: PGFITLILNL FTAYNYDISS YNFNDIASYP SLKYIGEFNR GSRTKIFSFI VHKNMVGLIF
601: DKLFYKLYES LGIILVGIET NTTNYYINNK KHKNKNSYVD DNFTTMRKNN MKNKKKKSFK
661: FIYLHLLKKY GHTNHYTQKK KKKKYDNIIN HHGSKSKMEY STQLRHNNKT IKIYDEYNTI
721: ETYQNYLNYE TINNSRINIY NSDEKKKKYN DVSPTNNILT NYKNGKLHIE KRDDFDNNNN
781: NNNNNIVKSR KKGRENKNDE IINVCININS DIKKKYNNNN NNNNNNDNDN NNIINDHDNY
841: NIYNNLNSNL KCRCLPNTKK NKAQNVNNVT NNKDNDVSVK RIKTHLQDDN TIDNKKELKC
901: YLNLLGKNYA IRDSDKCVVI ANSRKVIKYL SKAKSLFWIF EIKSKKKDNI SYDLKSVIKT
961: KQTFNKYFTT NIKKKLPTTS IQNNVYVNKN AHIIAMNYHD LFNTYRISRI FTKNNYNYKR
1021: KNSRKKHLFR NLNGEFNETK LYHHCNNTHN IKTTDKKNME KLDKLYFSTK LNSKSNTNIH
1081: IHNNNNNNNN NNEHYDDEIK TYYFNLTEKN SHLLLNYKKQ LKKKNYINTC YSVNKSDESI
1141: NKIKNMNSDN NNINSNNINS NINNNNNNNT KLNHTLKNRI TFSYMEACEK YFPTENRNNK
1201: LLLIINCTCN IIQLIKMFNN KYKYNVIILT DEIPTMNIMD LFKYNVVFIK CKILDDYNLI
1261: NSGLMNAEYI LILPTEAKNI NEINEIDMNT IIVTRKITHL LKKKKRTYYI NNIITELINP
1321: SNVIFLEENK MIKLKDKKSS YDDFFPYVNS SQFYSSNIIC ETMLYNFMTH HKSFTDFSVC
1381: TNTLECLIKF LRIIYICDLS KYYDFSFKKI KTFRDLFYFL SKKNIITIGL YRKGDKKVPF
1441: YIYTKPNENC LLRFDDIVYI L