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1.A.1.4.4
Guard cell outward rectifying K+ out channel, GORK, controls leaf stomatal pore opening (by increasing solute content) and closing (by decreasing solute content), which in turn controls gas and water loss (Schroeder, 2003). H2S signaling not only activates the ion channel proteins located in the guard cell membrane to induce stomatal closure, but also regulates the transcriptional expression and the activity of RuBisCO, a non-stomatal factor to enhance the photosynthetic efficiency of leaves. There is therefore a beneficial balance between the regulation of H2S signaling on stomatal factors and non-stomatal factors due to drought stress (Zhang et al. 2023).

Accession Number:Q94A76
Protein Name:Potassium channel GORK
Length:820
Molecular Weight:94461.00
Species: [3702]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate potassium(1+)

Cross database links:

RefSeq: NP_198566.2   
Entrez Gene ID: 833728   
Pfam: PF00023    PF00027    PF11834    PF00520   
KEGG: ath:AT5G37500   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005634 C:nucleus
GO:0015271 F:outward rectifier potassium channel activity
GO:0005515 F:protein binding
GO:0006813 P:potassium ion transport
GO:0009737 P:response to abscisic acid stimulus
GO:0009409 P:response to cold
GO:0009753 P:response to jasmonic acid stimulus
GO:0009414 P:response to water deprivation
GO:0055085 P:transmembrane transport

References (6)

[1] “GORK, a delayed outward rectifier expressed in guard cells of Arabidopsis thaliana, is a K(+)-selective, K(+)-sensing ion channel.”  Ache P.et.al.   11113445
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “K(+) channel profile and electrical properties of Arabidopsis root hairs.”  Ivashikina N.et.al.   11728473
[4] “Phylogenetic relationships within cation transporter families of Arabidopsis.”  Maeser P.et.al.   11500563
[5] “The Arabidopsis outward K(+) channel GORK is involved in regulation of stomatal movements and plant transpiration.”  Hosy E.et.al.   12671068
[6] “Regulation of the ABA-sensitive Arabidopsis potassium channel gene GORK in response to water stress.”  Becker D.et.al.   14596925

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGRLRRRQEI IDHEEEESND DVSSRRGKLS LAETFRWLDS SEHRRIETDG HNDYKYIIHP 
61:	KNRWYKAWEM FILVWAIYSS LFTPMEFGFF RGLPERLFVL DIVGQIAFLV DIVLQFFVAY 
121:	RDTQTYRTVY KPTRIAFRYL KSHFLMDFIG CFPWDLIYKA SGKHELVRYL LWIRLFRVRK 
181:	VVEFFQRLEK DTRINYLFTR ILKLLFVEVY CTHTAACIFY YLATTLPPEN EGYTWIGSLK 
241:	LGDYSYENFR EIDLWKRYTT ALYFAIVTMA TVGYGDIHAV NLREMIFVMI YVSFDMVLGA 
301:	YLIGNITALI VKGSNTERFR DKMNDLISFM NRKKLGRDLR SQITGHVRLQ YDSHYTDTVM 
361:	LQDIPASIRA KIAQLLYLPY IKKVPLFKGC STEFINQIVI RLHEEYFLPG EVITEQGNVV 
421:	DHLYFVCEGL LEALVTKTDG SEESVTLLGP HTSFGDISII CNISQPFTVR VCELCHLLRL 
481:	DKQSFSNILE IYFHDGRTIL NNIMEEKESN DRIKKLESDI VIHIGKQEAE LALKVNSAAF 
541:	QGDFYQLKSL IRSGADPNKT DYDGRSPLHL AACRGYEDIT LFLIQEGVDV NLKDKFGHTP 
601:	LFEAVKAGQE GVIGLLVKEG ASFNLEDSGN FLCTTVAKGD SDFLKRLLSS GMNPNSEDYD 
661:	HRTPLHVAAS EGLFLMAKML VEAGASVISK DRWGNSPLDE ARLCGNKKLI KLLEDVKNAQ 
721:	SSIYPSSLRE LQEERIERRK CTVFPFHPQE AKEERSRKHG VVVWIPSNLE KLIVTAAKEL 
781:	GLSDGASFVL LSEDQGRITD IDMISDGHKL YMISDTTDQT