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1.A.1.4.5
Root stelar K+ outward rectifying channel, SKOR (involved in K+ release into the xylem sap; part of the plant water stress response) (Gaymard et al., 1998). SKOR is an outwardly rectifying K+ channel that mediates the delivery of K+ from stelar cells to the xylem in the roots, a critical step in the long-distance distribution of K+ from roots to the upper parts of the plant. Liu et al. 2006 and Johansson et al. 2006 reported that SKOR channel activity is strictly dependent on intracellular and extracellular K+ concentrations. Activation by K+ did not affect the kinetics of voltage dependence, indicating that a voltage-independent gating mechanism underlies K+ sensing. The C-terminal non-transmembrane region is required for sensing. The intracellular K+ sensing mechanism couples SKOR activity to the K+ status of the 'source cells', thereby establishing a supply-based unloading system for the regulation of K+ distribution (Liu et al. 2006; Johansson et al. 2006). SKOR may be involved in droght resistance in barley (Cai et al. 2019).

Accession Number:Q9M8S6
Protein Name:Potassium channel SKOR aka Stelar K(+) outward rectifying channel
Length:828
Molecular Weight:93899.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate potassium(1+)

Cross database links:

RefSeq: NP_186934.1   
Entrez Gene ID: 821052   
Pfam: PF00023    PF00027    PF11834    PF00520   
BioCyc: MetaCyc:MONOMER-14560   
KEGG: ath:AT3G02850   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005249 F:voltage-gated potassium channel activity
GO:0006813 P:potassium ion transport
GO:0055085 P:transmembrane transport

References (5)

[1] “Identification and disruption of a plant shaker-like outward channel involved in K+ release into the xylem sap.”  Gaymard F.et.al.   9741629
[2] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[3] “pH control of the plant outwardly-rectifying potassium channel SKOR.”  Lacombe B.et.al.   10682858
[4] “Phylogenetic relationships within cation transporter families of Arabidopsis.”  Maeser P.et.al.   11500563
[5] “Regulated expression of Arabidopsis shaker K(+) channel genes involved in K(+) uptake and distribution in the plant.”  Pilot G.et.al.   12678562

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MGGSSGGGVS YRSGGESDVE LEDYEVDDFR DGIVESRGNR FNPLTNFLGL DFAGGSGGKF 
61:	TVINGIRDIS RGSIVHPDNR WYKAWTMFIL IWALYSSFFT PLEFGFFRGL PENLFILDIA 
121:	GQIAFLVDIV LTFFVAYRDS RTYRMIYKRS SIALRYLKST FIIDLLACMP WDIIYKAAGE 
181:	KEEVRYLLLI RLYRVHRVIL FFHKMEKDIR INYLFTRIVK LIFVELYCTH TAACIFYYLA 
241:	TTLPASQEGY TWIGSLKLGD YSYSKFREID LWTRYTTSMY FAVVTMATVG YGDIHAVNMR 
301:	EMIFAMVYIS FDMILGAYLI GNMTALIVKG SKTERFRDKM ADIMRYMNRN KLGRNIRGQI 
361:	TGHLRLQYES SYTEAAVLQD IPVSIRAKIA QTLYLPYIEK VPLFRGCSSE FINQIVIRLH 
421:	EEFFLPGEVI MEQGSVVDQL YFVCHGVLEE IGITKDGSEE IVAVLQPDHS FGEISILCNI 
481:	PQPYTVRVAE LCRILRLDKQ SFMNILEIFF HDGRRILNNL LEGKESNVRI KQLESDITFH 
541:	ISKQEAELAL KLNSAAFYGD LYQLKSLIRA GGDPNKTDYD GRSPLHLAAS RGYEDITLYL 
601:	IQESVDVNIK DKLGSTPLLE AIKNGNDRVA ALLVKEGATL NIENAGTFLC TVVAKGDSDF 
661:	LKRLLSNGID PNSKDYDHRT PLHVAASEGF YVLAIQLVEA SANVLAKDRW GNTPLDEALG 
721:	CGNKMLIKLL EDAKNSQISS FPSGSKEPKD KVYKKKCTVY FSHPGDSKEK RRRGIVLWVP 
781:	RSIEELIRTA KEQLNVPEAS CVLSEDEAKI IDVDLISDGQ KLYLAVET