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1.A.1.4.8 Inward rectifying Shaker K⁺ channel SPIK (AKT6) (expressed in pollen, and involved in pollen tube development) (Mouline et al., 2002). The shaker potassium Channel family includes 24 members in Gossypium hirsutum L. (cotton) (Wang et al. 2023).
Accession Number:	Q8GXE6
Protein Name:	SPIK aka AKT6
Length:	888
Molecular Weight:	99215.00
Species:	Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	potassium(1+)

Pfam:	PF00023 PF00027 PF11834 PF00520
Gene Ontology GO:0016021 C:integral to membrane GO:0005249 F:voltage-gated potassium channel activity GO:0006813 P:potassium ion transport GO:0055085 P:transmembrane transport
References (5) [1] “Pollen tube development and competitive ability are impaired by disruption of a Shaker K(+) channel in Arabidopsis.” Mouline K.et.al. 11825875 [2] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.” Lin X.et.al. 10617197 [3] “Functional annotation of a full-length Arabidopsis cDNA collection.” Seki M.et.al. 11910074 [4] “A shaker-like K(+) channel with weak rectification is expressed in both source and sink phloem tissues of Arabidopsis.” Lacombe B.et.al. 10852932 [5] “Phylogenetic relationships within cation transporter families of Arabidopsis.” Maeser P.et.al. 11500563

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MEKKKVWFWG VKDDGEGGGG RGGGRTKDAE DDVADHLSRD GTMSQYSLSK GLLPSLGANN 
61:	RSSRDVILPR FIVSPFDPRY RAWETFLVFL VLYTAWASPF EFGFLQKPRP PLSILDNIVN 
121:	GFFAVDIVLT FFVAFLDKVT YLLVDDPKRI AWRYASTWLI FDVVSTFPYE IFGSLLHESI 
181:	QGYGIFSMLR LWRLRRVSNC FARLEKDRKY SYFWVRCSKL LLVTLFVIHC GACFLYSIAA 
241:	HYPDPSKTFM ALTDENWKES PIAVRYNTAM YWSITTFSTT GYGDIHGVNS REMTFILFYM 
301:	VFNLGLSAYI IGNMTNLVVH VTGRTRKFRD TIQAASGFGQ RNNLPVRLQD QMVAHLCLRY 
361:	RTDSEGLQQQ EIIDSLPKAI RSSISHYLFY EVVDKIYLFH GISNDLLFQL VTEMKAEYFP 
421:	PKEDVILQNE APTDFYILVT GAVDIIARVN GVEQVVSEAQ RGHVFGEVGV LCYRPQLFTV 
481:	RTKRLSQLLR LNRTVLLNLV QANVGDGAII MNNLLQHLKD SEDPVMKGVL ADTEHMLAQG 
541:	KMDLPLSLCF AAARGDDLLL HQLLRRGSSP NEMDKDGRTA LHIAASKGSH YCVVLLLEHG 
601:	ADPNIRDSEG NVPLWEAIIG RHREIAKLLA ENGAKLSLDS VSYFSGLAVE KNCLDALKDI 
661:	IKYGGDVTLP DGNGTTALHR AVSEGHLEIV KFLLDQGADL DWPDSYGWTP RGLADHQGNE 
721:	EIKTLFHNHR PVEKKPKPIP GIPQSPVTGK PLMKYSSEPT MHSGELVLDG GQVVVSQKRK 
781:	LNNFRNSLFG IISAANSADD GGEVPRSPAV PGGGGSMIYP ERVTISSPEN GETGGKVVLL 
841:	PNSMEELLKI GENKMGFVPT KVLTREGAEI DDITLIRDGD FLLLSRDP

1.A.1.4.8
Inward rectifying Shaker K⁺ channel SPIK (AKT6) (expressed in pollen, and involved in pollen tube development) (Mouline et al., 2002). The shaker potassium Channel family includes 24 members in Gossypium hirsutum L. (cotton) (Wang et al. 2023).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

1.A.1.4.8Inward rectifying Shaker K+ channel SPIK (AKT6) (expressed in pollen, and involved in pollen tube development) (Mouline et al., 2002). The shaker potassium Channel family includes 24 members in Gossypium hirsutum L. (cotton) (Wang et al. 2023).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

1.A.1.4.8
Inward rectifying Shaker K⁺ channel SPIK (AKT6) (expressed in pollen, and involved in pollen tube development) (Mouline et al., 2002). The shaker potassium Channel family includes 24 members in Gossypium hirsutum L. (cotton) (Wang et al. 2023).