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| Accession Number: | O65718 |
| Protein Name: | Cyclic nucleotide-gated ion channel 2 aka CNGC2 |
| Length: | 726 |
| Molecular Weight: | 83241.00 |
| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
| Number of TMSs: | 6 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | potassium(1+), rubidium(1+), caesium(1+) |
Cross database links:
| RefSeq: | NP_197045.1 |
|---|---|
| Entrez Gene ID: | 831393 |
| Pfam: | PF00027 |
| KEGG: | ath:AT5G15410 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005262
F:calcium channel activity
GO:0005516
F:calmodulin binding
GO:0030552
F:cAMP binding
GO:0030553
F:cGMP binding
GO:0005222
F:intracellular cAMP activated cation channel...
GO:0005242
F:inward rectifier potassium channel activity
GO:0006811
P:ion transport
GO:0007263
P:nitric oxide mediated signal transduction
GO:0009626
P:plant-type hypersensitive response
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References (8)[1] “Cloning and first functional characterization of a plant cyclic nucleotide-gated cation channel.” Leng Q.et.al. 10557223 [2] “The Arabidopsis dnd1 'defense, no death' gene encodes a mutated cyclic nucleotide-gated ion channel.” Clough S.J.et.al. 10900264 [3] “Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.” Tabata S.et.al. 11130714 [4] “Characterisation of a novel gene family of putative cyclic nucleotide- and calmodulin-regulated ion channels in Arabidopsis thaliana.” Koehler C.et.al. 10341447 [5] “Characterisation of calmodulin binding to cyclic nucleotide-gated ion channels from Arabidopsis thaliana.” Koehler C.et.al. 10767408 [6] “Developmentally regulated expression of a cyclic nucleotide-gated ion channel from Arabidopsis indicates its involvement in programmed cell death.” Koehler C.et.al. 11506354 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MPSHPNFIFR WIGLFSDKFR RQTTGIDENS NLQINGGDSS SSGSDETPVL SSVECYACTQ 61: VGVPAFHSTS CDQAHAPEWR ASAGSSLVPI QEGSVPNPAR TRFRRLKGPF GEVLDPRSKR 121: VQRWNRALLL ARGMALAVDP LFFYALSIGR TTGPACLYMD GAFAAVVTVL RTCLDAVHLW 181: HVWLQFRLAY VSRESLVVGC GKLVWDPRAI ASHYARSLTG FWFDVIVILP VPQAVFWLVV 241: PKLIREEKVK LIMTILLLIF LFQFLPKIYH CICLMRRMQK VTGYIFGTIW WGFALNLIAY 301: FIASHVAGGC WYVLAIQRVA SCIRQQCMRT GNCNLSLACK EEVCYQFVSP TSTVGYPCLS 361: GNLTSVVNKP MCLDSNGPFR YGIYRWALPV ISSNSLAVKI LYPIFWGLMT LSTFANDLEP 421: TSNWLEVIFS IVMVLSGLLL FTLLIGNIQV FLHAVMAKKR KMQIRCRDME WWMKRRQLPS 481: RLRQRVRRFE RQRWNALGGE DELELIHDLP PGLRRDIKRY LCFDLINKVP LFRGMDDLIL 541: DNICDRAKPR VFSKDEKIIR EGDPVQRMIF IMRGRVKRIQ SLSKGVLATS TLEPGGYLGD 601: ELLSWCLRRP FLDRLPPSSA TFVCLENIEA FSLGSEDLRY ITDHFRYKFA NERLKRTARY 661: YSSNWRTWAA VNIQMAWRRR RKRTRGENIG GSMSPVSENS IEGNSERRLL QYAAMFMSIR 721: PHDHLE