1.A.10.1.19
Olfactory glutamate-like ionotropic receptor, kainate 2 isoform X1 of 754 aas and 4 TMSs. Chen et al. 2017 identify 102 putative IR genes, (dubbed AalbIr genes) in the mosquito Aedes albopictus (Skuse), 19 of which showed expression in the female antenna. These putative olfactory AalbIRs share four conservative hydrophobic domains similar to the transmembrane and ion channel pore regions found in conventional iGluRs. To determine their potential functions in host-seeking, Chen et al. 2017 compared their transcript expression levels in the antennae of blood-fed females with that of non-blood-fed females. Three AalbIr genes showed downregulation when the mosquito finished a bloodmeal.
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| Accession Number: | XP_019931100.1 |
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| Protein Name: | XP_019931100.1 PREDICTED: glutamate receptor ionotropic, kainate 2 isoform X1 [Aedes albopictus] |
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| Length: | 755 |
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| Molecular Weight: | |
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| Species: | Aedes albopictus [7160] |
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| Number of TMSs: | 5 |
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| Substrate |
inorganic cation, calcium(2+), sodium(1+), potassium(1+) |
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1: MEIPHLETRW DYRLRRESCL VNLYPHPSTL SKAYVDLVAA WGWKSFTIIY ETNEGLVRMQ
61: ELLKAHGLSE YPITVRQLSD SGDYRPLLKQ IKNSAESHIV LDCTTEKIYE VLKQAQQIGM
121: MSDYHSYLIT SLDLHTISLD EFKYGGTNIT AFRLVDPENP EVAQAIHNWT LGEARLGKKI
181: DFKTTENVTV IKAETALMYD AVHLFAKALH DLDTSQQIDI HPLSCDAQDT WPHGYSLINY
241: MKIVEMRGLT DVIKFDHQGF RSDFVLDIVE LGPQGLRKSG TWNSTSGVNF TRSYGEQQKE
301: IVEILQNKTL IVTTILSSPY CMRKDSAEKL TGNSQFEGYA IDLIHEVSKI LGFNYTIRLA
361: PDGRYGSQNK ETLEWDGMIK ELLEQRADLA IADLTITFDR EQVVDFTMPF MNLGISVLYR
421: KPVKQPPNLF SFLSPLSLDV WIYMATAYLG VSVLLFILAR FTPYEWPTPN PCDPHPEKLQ
481: TQFTLMNCMW FAIGSLMQQG CDFLPKAVST RMVAGMWWFF TLIMISSYTA NLAAFLTVER
541: MDSPIESAED LAKQTKIKYG ALRGGSTAAF FRDSNFSTYQ RMWSFMESTR PSVFTASNIE
601: GVERVVKGKG SYAFLMESTS IEYVIERNCE LTQVGGMLDS KGYGIAMPPN SPFRTAISGA
661: VLKLQEEGKL HILKTRWWKE KRGGGSCRDE TSKSSSTANE LGLANVGGVF VVLMGGMGVA
721: CVIAVCEFVW KSRKVAVEER EPYQKKHPKE CRFE