1.A.10.1.29 Fusion protein with an N-terminal glycine receptor/chloride channel domain (residues 1 - 470) like 1.A.9.3.1 and a C-terminal glutamate receptor/cation channel domain (residues 500 to the end) like 1.A.10.1.13. This fusion protein is from Tupaia chinensis (chinese tree shrew), and the two domains are 93.8% and 97.4% identical to the two proteins (both from Homo sapiens) that they hit in TCDB as noted above. It should be noted that the fusion proteins reported here and in TC#s 1.A.10.1.20 - 23 could reflect the presence of true fusion proteins, or they could be a result of sequencing errors.
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Accession Number: | ELV12724.1 |
Protein Name: | ELV12724.1 Glutamate receptor 2 [Tupaia chinensis] |
Length: | 1376 |
Molecular Weight: | |
Species: | Tupaia chinensis [246437] |
Number of TMSs: | 9 |
Substrate |
anion, chloride, cation, calcium ion, sodium(1+), potassium(1+) |
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1: MRTAVPTSDP TASPHEDNCL HLGPHSLTPQ QSAEDLARVP ANSTSNILNR LLVSYDPRIR
61: PNFKGLQSHT CSVSPQDYRV NIFLRQKWND PRLKLPSDFR GSDALTVDPT MYKCLWKPDL
121: FFANEKSANF HDVTQENILL FIFRDGDVLV SMRLSITLSC PLDLTLFPMD TQRCKMQLES
181: FGYTTDDLRF IWQSGDPVQL EKIALPQFDI KKEDIEYGNC TKYYKGTGYY TCVEVIFTLR
241: RQVGFYMMGV YAPTLLIVVL SWLSFWINPD ASAARVPLGI FSVLSLASEC TTLAAELPKV
301: SYVKALDVWL IACLLFGFAS LVEYAVVQVM LNNPKRVEAE KARIAKAEQA EGKGGSAAKK
361: STVNGTGTPV HISTLQVGET RCKKVCTSKS DLRSNDFSIV GSLPRDFELS NYDCYGKPIE
421: VSNGLSKSQA KNNKKPPPAK PVIPTAAKRI DLYARALFPF CFLFFNVIYW DTRRLSIPHA
481: KTSRHLSVSA ADNSDPDAVH AKSRDGHQAG GLFPRGADQE YSAFRVGMVQ FSTSEFRLTP
541: HIDNLEVANS FAVTNAFCSQ FSRGVYAIFG FYDKKSVNTI TSFCGTLHVS FITPSFPTDG
601: THPFVIQMRP DLKGALLSLI EYYQWDKFAY LYDSDRGLST LQAVLDSAAE KKWQVTAINV
661: GNINNDKKDE TYRSLFQDLE LKKERRVVLD CERDKVNDIV DQVITIGKHV KGYHYIIANL
721: GFTDGDLLKI QFGGANVSGF QIVDYDDSLV SKFIERWSTL EEKEYPGAHT ATIKYTSALT
781: YDAVQVMTEA FRNLRKQRIE ISRRGNAGDC LANPAVPWGQ GVEIERALKQ VQVEGLSGNI
841: KFDQNGKRIN YTINIMELKT NGPRKVLASR KVFDVFQIGY WSEVDKMVVT LTELPSGNDT
901: SGLENKTVVV TTILESPYVM MKKNHEMLEG NERYEGYCVD LAAEIAKHCG FKYKLTIVGD
961: GKYGARDADT KIWNGMVGEL VYGKADIAIA PLTITLVREE VIDFSKPFMS LGISIMIKKP
1021: QKSKPGVFSF LDPLAYEIWM CIVFAYIGVS VVLFLVSRFS PYEWHTEEFE DGRETQTSES
1081: TNEFGIFNSL WFSLGAFMQQ GCDISPRSLS GRIVGGVWWF FTLIIISSYT ANLAAFLTVE
1141: RMVSPIESAE DLSKQTEIAY GTLDSGSTKE FFRRSKIAVF DKMWTYMRSA EPSVFVRTTA
1201: EGVARVRKSK GKYAYLLEST MNEYIEQRKP CDTMKVGGNL DSKGYGIATP KGSSLRNAVN
1261: LAVLKLNEQG LLDKLKNKWW YDKGECGSGG GDSKEKTSAL SLSNVAGVFY ILVGGLGLAM
1321: LVALIEFCYK SRAEAKRMKV AKNTQTINPS SSQNSQNFAT YKEGYNVYGI ESVKI