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|---|---|
| Accession Number: | P0AAC6 |
| Protein Name: | Inner membrane protein YccA aka B0970 |
| Length: | 219 |
| Molecular Weight: | 23363.00 |
| Species: | Escherichia coli [83333] |
| Number of TMSs: | 7 |
| Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Multi-pass membrane protein2 |
| Substrate | Unknown, cations |
Cross database links:
| Genevestigator: | P0AAC6 P0AAC6 P0AAC6 |
|---|---|
| EchoBASE: | EB1104 EB1104 EB1104 |
| EcoGene: | EG11113 EG11113 EG11113 |
| eggNOG: | COG0670 COG0670 COG0670 |
| HEGENOM: | HBG595196 HBG595196 HBG595196 |
| DIP: | DIP-47918N DIP-47918N DIP-47918N |
| RefSeq: | AP_001600.1 NP_415490.1 |
| Entrez Gene ID: | 946016 |
| Pfam: | PF01027 |
| BioCyc: | EcoCyc:EG11113-MONOMER ECOL168927:B0970-MONOMER |
| KEGG: | ecj:JW0953 eco:b0970 ecj:JW0953 eco:b0970 ecj:JW0953 eco:b0970 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0043066
P:negative regulation of apoptosis
GO:0030162
P:regulation of proteolysis
GO:0043066
P:negative regulation of apoptotic process
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References (23)[1] “The E. coli divE mutation, which differentially inhibits synthesis of certain proteins, is in tRNASer1.” Tamura F.et.al. 6376117 [2] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.” Oshima T.et.al. 8905232 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996 [6] “The E. coli divE mutation, which differentially inhibits synthesis of certain proteins, is in tRNASer1.” Tamura F.et.al. 6376117 [7] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.” Oshima T.et.al. 8905232 [8] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [9] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [10] “Different pathways for protein degradation by the FtsH/HflKC membrane-embedded protease complex: an implication from the interference by a mutant form of a new substrate protein, YccA.” Kihara A.et.al. 9636708 [11] “Dislocation of membrane proteins in FtsH-mediated proteolysis.” Kihara A.et.al. 10357810 [12] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996 [13] “Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY.” van Stelten J.et.al. 19661432 [14] “Quality control of cytoplasmic membrane proteins in Escherichia coli.” Akiyama Y.et.al. 19454621 [15] “The E. coli divE mutation, which differentially inhibits synthesis of certain proteins, is in tRNASer1.” Tamura F.et.al. 6376117 [16] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.” Oshima T.et.al. 8905232 [17] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [18] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [19] “Different pathways for protein degradation by the FtsH/HflKC membrane-embedded protease complex: an implication from the interference by a mutant form of a new substrate protein, YccA.” Kihara A.et.al. 9636708 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MDRIVSSSHD RTSLLSTHKV LRNTYFLLSL TLAFSAITAT ASTVLMLPSP GLILTLVGMY 61: GLMFLTYKTA NKPTGIISAF AFTGFLGYIL GPILNTYLSA GMGDVIAMAL GGTALVFFCC 121: SAYVLTTRKD MSFLGGMLMA GIVVVLIGMV ANIFLQLPAL HLAISAVFIL ISSGAILFET 181: SNIIHGGETN YIRATVSLYV SLYNIFVSLL SILGFASRD