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1.A.14.3.12 Viroporin, pUS21, of 243 aas and 8 TMSs. It modulates calcium ion homeostasis and protects cells against apoptosis (Luganini et al. 2018). pUS21 of HCMV constitutes a TMBIM-derived viroporin that may contribute to HCMV's overall strategy to counteract apoptosis of infected cells.
Accession Number:	F5HHT6
Protein Name:	Membrane protein US21
Length:	243
Molecular Weight:	26927.00
Species:	Human cytomegalovirus (strain Merlin) (HHV-5) [295027]
Number of TMSs:	8
Location¹ / Topology² / Orientation³:	Host membrane¹ / Multi-pass membrane protein²
Substrate

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FASTA formatted sequence

1:	MSLRGQVQIA RSVFLLRIYI LIWVQCLILM SVCAFCWLVL PHRLEQLFSS VRLTLSCLMI 
61:	SIVCLGLLRW AEPNFPKNVW ILLTYTLLTS VAVTASGFHF SHRSVIYAMV ATVTLFCFLT 
121:	LATYLFARDV ELQRSLLTGA STLILLLFAV FSLFPEAVSE ILVMIAGLAV IVTSVVCDTQ 
181:	DILHDIEYES YIPGALCLYM DLMYLFVSVL YFMPSEPGSA HTAQTTVAAT VAATAAASPQ 
241:	FVS

1.A.14.3.12
Viroporin, pUS21, of 243 aas and 8 TMSs. It modulates calcium ion homeostasis and protects cells against apoptosis (Luganini et al. 2018). pUS21 of HCMV constitutes a TMBIM-derived viroporin that may contribute to HCMV's overall strategy to counteract apoptosis of infected cells.

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1.A.14.3.12Viroporin, pUS21, of 243 aas and 8 TMSs. It modulates calcium ion homeostasis and protects cells against apoptosis (Luganini et al. 2018). pUS21 of HCMV constitutes a TMBIM-derived viroporin that may contribute to HCMV's overall strategy to counteract apoptosis of infected cells.

Cross database links:

External Searches:

Analyze:

1.A.14.3.12
Viroporin, pUS21, of 243 aas and 8 TMSs. It modulates calcium ion homeostasis and protects cells against apoptosis (Luganini et al. 2018). pUS21 of HCMV constitutes a TMBIM-derived viroporin that may contribute to HCMV's overall strategy to counteract apoptosis of infected cells.