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1.A.143.  The A15.5L Viroporin (A15.5L-VP) Family 

This family has been examined, first, showing that its characterized member is a  small transmembrane protein of 53 aas and 2 TMS (residues 7 - 24 and 30 - 50). Second, it has been shown to have ion channel activity (Basu et al. 2023). Third, its 3-D transmembrane structure has been predicted using alpha-fold.

References associated with 1.A.143 family:

Basu, K., M. Krugliak, and I.T. Arkin. (2023). Viroporins of Mpox Virus. Int J Mol Sci 24:. 37762131