1.A.23.3.5
Small-conductance mechanosensitive channel Msc1 of 533 aas and 5 TMSs in a 4 (N-terminus) + 1 TMS (near the C-terminus) with two smaller peaks of hydrophobicity between these that could be TMSs. This system as well as a second Msc protein, Msc2, are able to export L-glutamate and other metabolites (Kawasaki and Martinac 2020).
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| Accession Number: | GAV97011.1 |
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| Protein Name: | GAV97011.1 small-conductance mechanosensitive channel Msc1 [Corynebacterium glutamicum] |
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| Length: | 534 |
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| Molecular Weight: | |
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| Species: | Corynebacterium glutamicum [1718] |
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| Number of TMSs: | 6 |
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| Substrate |
salt, L-glutamate(1-), metabolite |
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1: MILGVPIQYL LYSLWNWIVD TGFDVAIILV LAFLIPRIGR LAMRIIKRRV ESAADADTTK
61: NQLAFAGVGV YIAQIVAFFM LAVSAMQAFG FSLAGAAIPA TIASAAIGLG AQSIVADFLA
121: GFFILTEKQF GVGDWVRFEG NGIVVEGTVI EITMRATKIR TIAQETVIIP NSTAKVCINN
181: SNNWSRAVVV IPIPMLGSEN ITDVIARSEA ATRRALGQEK IAPEILGELD VHPATEVTPP
241: TVVGMPWMVT MRFLVQVTAG NQWLVERAIR TEIISEFWEE YGSATTTSGT LIDSLHVAHE
301: EPKTSLIDAS PQALKEPKPE AAATVASLAA SSNDDADNAD ASVINAGNPE KELDSDVLEQ
361: ELSSEEPEET AKPDHSLRGF FRTDYYPNRW QKILSFGGRV RMSTSLLLGA LLLLSLFKVM
421: TVEPSENWQN SSGWLSPSTA TSTAVTTSET SAPASTPSMT VPTTVEETPT MESNVETQQE
481: TSTPATATPQ RADTIEPTEE ATSQEETTAS QTQSPAVEAP TAVQETVAPT STP