1.A.3.1.7 Aphid ryanodine receptor RyR) of 5105 aas and 6 TMSs, a target of insecticides. The sequence of the Acyrthosiphon pisum (Pea aphid) is provided below, but the Toxoptera citricida (98% identiy; Brown citrus aphid; Aphis citricidus) RyR was studied (Wang et al. 2015).
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Accession Number: | X1WXB1 |
Protein Name: | Uncharacterized protein |
Length: | 5101 |
Molecular Weight: | 579963.00 |
Species: | Acyrthosiphon pisum (Pea aphid) [7029] |
Number of TMSs: | 6 |
Substrate |
calcium(2+) |
---|
1: MADSEGSSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCYLENI ADKNIPPDLS
61: QCVFVIEQAL SVRALQELVT AASSQEGKGG TGSGHRTLLY GNAILLRHQN SDMYLACLST
121: SSSNDKLSFD VGLQEHSQGE ACWWTVHPAS KQRSEGEKVR VGDDLILVSV ATERYLHTAK
181: ENELSVVNAS FHVTHWSVQP YGTGISRMKY VGYVFGGDVL RFFHGGDECL TIPSSWSDVS
241: GQNIVIYEGG SVMSQARSLW RLELARTKWA GGFINWYHPM RIRHLTTGRY LGVNENNELH
301: LVCREEATTA SSTFFLRQEK DDQKIILEDK DLEVIGAPII KYGDSTVLVQ HSDTGLWLTY
361: KSYETKKKGV GKVEEKQAVL HEEGKMDDGL DFSRSQEEES RTARVIRKCS SLFTQFISGL
421: ENLQSNRRSS LFCSFVNLNE MVMCLEDLIN YFAQPEEDME HEEKQNRFRA LRNRQDLFQE
481: EGILNLILEA IDKVNIITSQ GFMVSLAGDE SGQSWDVISG YLYQLLAAII KGNHTNCAQF
541: ANTNRLNWLF SRLGSQASSE GTGMLDVLHC VLIDSPEALN MMKDEHIKVI ISLLEKHGRD
601: PKVLDVLCSL CVGNGVAVRS SQNNICDFLL PGKNLLLQTL LVDHVASVRP NIFVGHVSGS
661: AVYRKWYYEV AIDHVEQTTH LNPHIRIGWA NTAGYVPYPG GGEKWGGNGV GDDLYSFGFD
721: GSYLWTGGRK SEVMPGTQIS NIKKSDVIGC ALDLTIPIIT FTLNGQLVQG AFRDFNLDGM
781: FFPVISCSSK VSCRFLLGGD HGRLKFTPPD EFSPLFETLL PQQILTIDPC FYFGNLNKCV
841: LTGPWYVEDD TAFVPNPVDT SMVTLPSYIE NIKDKLAENI HEMWAMNKIE AGWQYGDKRN
901: DTRKFHPCLI QFDKLPPAEK RYDSQLAVQT LKTVIALGYH ISIDNPPSRI KTVRLPNEPF
961: MQSNGYKPAP LDLSAIILSG KMEELIDQLA ENTHNLWAKE RIQQGWTYGL NEELQMLRSP
1021: HLVPYSKVDD AIKKANRDTA SETVRTLLVY GYNLDPPTGE TNEATLLTDD NTNRYLTFRT
1081: YRAEKTYAVS SGKWYFEFEI LTSGPMRVGW ARFTCSPGYQ IGSDENSWAF DGYNEEKIYM
1141: GTAESFGRQW QVGDVVGVFL DLMDHTISFS MNGELLMDTL GGETTFSEVQ GEGFVPAFTL
1201: GLGQKAKLTF GQDVNSLKYF TTCGLQEGYE PFCVNMKRPV TYWYTKDQPI FENTDDFSSV
1261: IDVTRIPAGS DTPPCLKISH NTFETMEKAN WEFLRLSLPV ICLPSFIDEQ EKQRRWQEIR
1321: IRQHRLLSQS EHATPAHIEQ IMKSGFSMSD IKGLHRGYSD DPVENDEMMP NATPLPPRGK
1381: NQPPPPRPPR KGSLSRHDDL TIENEGKLNR SSSELNFNIY NHQNGDGQDI NKDDKKKRGR
1441: SPFRFFSRKK EGPSDNPKRA KTPDPVRNVD RSRNAAHRPN TLNERVTPQI RVSQMDLKLV
1501: PPAIPDRPGG PKAMSFTPTS AGIEFVGNEI FDLECLKLIN EYYYGVRIFP GQDPTHVYVG
1561: WVTTQYHLHT KDFSQNHVRK STVTIVDEHN RILESIDRQS CYMVRSDELY NEVTNDSSGK
1621: GASQGMAIGC FIDIATGMMS FTCEGKETSF KFKMEPDIKL FPAIFVEASS KEILQIELGR
1681: TSTTLPLSAA VLQNSERHVL PQFPPRLKVQ CLRPHQWARV PNDSLHIHTL KLSDIRGWSI
1741: LCEDPVSMIA LHIPEEDRCI DILELIEMEK LLSFHAHTLT LYAAVCYQAN YRAAHILCTH
1801: VNQKQLLYAI CSEYMSGPLR QGFYDLLIAL HLESHATTME VCKNEYIIPL GHELTTLYDD
1861: PQMGHSLRSL QTESVRPQMK MTEISDVIDN VRNLYSPYFP LQVVREYVMA ALEEAVLVNQ
1921: VHNRDPIGGS NENLFLPLLK LVDRLLLVGM LRDEDVEKLL IMINPETWDP EFQKDGPDEH
1981: RKGLLHMKMA EGAKLQMCYL LHHLCDIQLR HRVESIISFS YQFVNDIQID QLRRYNEIKQ
2041: SDLPSAVAAK KTREFRCPPR EQMNAILGFK NLDSDDKENC LIGDDLRERM NEFNEKLMKQ
2101: ISLVALQESE DDKSDLNNLN NEGKIKQFYN FINAVKDEGN EDGLNEQEKK IPEEIFRKVL
2161: ISTIVSWAEE TQIETPKLVR EMFSLLVRQY DSVGELIRAL EKTYVINFKT KEDVAQMWVG
2221: LSQIRSLLPV QMSQEEEELM RERLWKLVNN HTFFQHPDLI RVLRMHENVM AVMMNTLGRR
2281: AQAQSQPGGT PVTGQDGEIV PKEKDTSHEM VVACCRFLCY FCRTSRQNQK AMFDHFSFLL
2341: ENSNILLSRP SLRGSTPLDV AYSSLMENTE LALALREHYL EKIAIYLSRC GLQSNSELIE
2401: KGYPDLGWDP VEGERYLDFL RFCVWVNGES VEENANLVIR LLIRRPECLG PALRGEGEGL
2461: LRAIIDANKM SERITERRKF LEESGNQENI QLDHPLPESD EDEDYIDTGA AILNFYCTLV
2521: DLLGRCAPDS SVISLGKNES LRARAILRSL VPLEDLHGVL SLRFTLQNPA AGQDRPKSDM
2581: PSGLIPGHKQ SVVLFLERVY GIEMQELFFT LLEEAFLPDL RTATMLDRND GLESDMALAM
2641: NRYIGNSVLP LLIGHSKFYS ESDNYANLLD ATLHTVYRLS KNRMLTKGQR EAVSDFLVAL
2701: TSQMQPSMLL KLLRKLTVDV SNLSEYTTVA LRLLTLHYDR CAKYYGSTGG QGIYGASSDE
2761: EKRLTMMLFS NIFDSLSKMD YDPELFGKAL PCLSAIGCAL PPDYSLSKNH DDEWYGSKQN
2821: IQGPSDGPYN PQPINTNSIV LDNDLNSIVH KFSEHYHDAW ANRKLENGWV YGEQFNDVNK
2881: SHPRLKPYMM LSEYEKELYK EPVRESLKAL LAIGWSIEHS ENDAPLNNRG SVRRQSKSNE
2941: NVTPFDYHPN PIDMTNLTLT REMQNMAERL AENSHDIWAK KKKEEVMLCG GGIHNQLVPY
3001: DLLTDKEKKK DRERSQEFLK YLQYQGYKLH RPNRNGGPSE AEQLAAASTG ELRFSYSLLE
3061: KLIHYIDRAS INMKLLKPSG TFSRRSSFKI CTRDIKFFSK VVLPLVEKYF STHRNYFITV
3121: ATASSVLGAA SLKEKEMVAS LFCKLANLLR SKLMAFGADV RITVRCLQVL VKAIDAKSLV
3181: KNCPEFIRTS MLTFFHNIAD DLEHTIQNLH DSRYCYLRGT HLKTSTSLFY VNDVILPVLS
3241: SLFDHLAAYE YGNELLLNEI QVAAYKMLSS LYTLGTDTSL THDRKYLKVQ LERHRPAFGS
3301: CLGAFSSTFP VAFLEPHLNK HNQYSLLNRF ADSSLEAQDI MSRMEGTMPT LETVLNEVDQ
3361: FIESEKTYAD APHIIDVILP LLCSYLPYWW AQGPDNVALT TGNHVTMVTS EHMNCLLKNV
3421: LKLIKKNIGN DNAPWMTQIA AYTQQIIINS SEELLKDPFL PLAERVKKRT ETLYHKEESL
3481: RGFIKSSTDD TSQIEAQIQE DWQLVVRDIY AFYPLLIKYV DLQRNHWLRN NISNAEDLYN
3541: HVSEIFNIWS KSQYFLREEQ NFISANEIDN MILIMPTATR RSAVISETSL GGSTGKKKKK
3601: HRDKKRDKEK EIQASLMVAC LKRLLPVGLN LFAGREQELV QHCKDRFLKR MPDYDVIQFV
3661: KIQLTLPDKL DPADEMSWQH YLYSKLGSKK GTTEIKPQQV DEVADRIVAM AKVLYGLHMI
3721: DHPQLQSKAI YRSVVSTQRK RAVIACFRQL SLHALTRHRA VNIFVRSFYE LWLQDENIGQ
3781: EVMIEDLTQS FEEAELKKRD KEEEEGMADP LNQMVTTFCR GAMTERSGAL QEDPLYMSYA
3841: DILAKSCGEE EEEGNNEEEG STGNGEEEGG ASIHEQEMEK QKLLFHQARL ANRGVAEMVL
3901: LHISACKGIP SEMVMKTLQL GIAVLRGGNL EIQMGMLNHL KEKKDVGFFT SVAGLMNSCS
3961: VLDLDAFERN TKAEGLGVGS EGAAGEKNMH DAEFTCTLFR FIQLTCEGHN LEWQNYLRTQ
4021: AGNTTTVNVV ICTVDYLLRL QESIMDFYWH YSSKELIDPA GKANFFKAIG VASQVFNTLS
4081: EVIQGPCTQN QQALAHSRLW DAVGGFLFLF SHMQDKLSKH SSQVDLLKEL LNLQKDMITM
4141: MLSMLEGNVV NGTIGKQMVD TLVESASNVE LILKYFDMFL KLKDLTSSAS FTEIDPNNDG
4201: WVHPKDFKEK MEQQKSYTAE EIEFMLQCCE SNHDGKIDYI GFTDQFHEPS KEIGFNLAVL
4261: LTNLSEHMPN EPRLTRFLET ASSVLNYFQP FLGRIEILGG SKRIERVYFE IKESNIEQWL
4321: KPQIRESKRA FFYSIVTEGG DKEKLEAFVN FCEDAIFEMQ HASGLMAVDD GSGIGGGKSR
4381: KTAYTYMADD EENKTAKDPI RRGIQAIKYG FHLLFFVLSP TNIKNKINEI QQMSVIELIT
4441: SFFKLWFYLI FYTGYSGVYV LRYISRILMQ LMSGTQSEET TVEVVEEKSG SFRMLPALPS
4501: SGMDEPPSTL TDGNNMRKNS GSPDSKHLKS NSVGDDKDET SAENHEKEDG VDGSEQQASF
4561: VDLLVGESAR KDSIAGPEVL AQQQAVMAAV EAEIKQKNSV ENPSAFSTID INAYTHRALS
4621: FLARNFYNLK YVALVLAFCI NFILLFYKVT TLADDLSDDG DVKEFALGSA GISNDDMDDS
4681: NSTEIADDEG VLELVHVNED FFYMAHVMRL AALLHSLASL AMLIAYYHLK VPLAIFKREK
4741: EIARRLEFDG LYIVEQPEDD DIKSHWDKLV ISAKSFPVNY WDKFAKKKVR QKYSETYDFD
4801: SISNLLGMEK TSFSTQENEE RTGLINFVIN IDWRYQVWKA GVTITDNAFL YSLWYFTFSI
4861: LGNFNNFFFA AHLLDVAVGF KTLRTILQSV THNGKQLVLT VLLLTIIVYI YTVIAFNFFR
4921: KFYVQEEDDE VDKKCHDMLT CFVFHLYKGV RAGGGIGDEI GSPDGDDYEV YRIMFDITFF
4981: FFVIIILLAI IQGLIIDAFG ELRDQLESVK EDMESNCFIC GIGKDYFDKV PHGFDTHVQE
5041: EHNLANYMFF LMHLINKPDT EYTGQETYVW NMYQQRCWDF FPVGDCFRKQ YEEELGGGGG
5101: V