1.A.3.2.11 Calcium release channel IV3b, CRCIV3b, of 3127 aas. Display structural and functional properties of ryanodine receptors (Ladenburger et al. 2009). Localized to the alveolar sacs of the cortical subplasmalemmal Ca2+-stores (Plattner et al. 2012). Involved in exocytosis in response to ryanodine receptor agonists (Docampo et al. 2013).
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Accession Number: | G7ZUA3 |
Protein Name: | Calcium-release channel IV-3b |
Length: | 3127 |
Molecular Weight: | 368989.00 |
Species: | Paramecium tetraurelia [5888] |
Number of TMSs: | 6 |
Substrate |
calcium(2+) |
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1: MTDLPPIPNL RKQSLLGAEN YIPQTHNIIP LPQIVENVKP QKRNFNLKVG DIIYFKSYLS
61: DDFKGVISGD GIASNKLECI QVLGKNKLQD VQSQKSLQCK VGSLSFQKSL FQIITGKKYL
121: YQNQYKEEKE KPIDTIREIA ADETYQMELD KLTSDYDKRL EEFQKKCEEE INENERLYNH
181: LYGSNIVYGQ EIQLLHIYSG CTLSLNSDIL AKENCCRELS LEEIPNLNSN FRILSMNSVK
241: NPGEPILYGD QIIVQNSNQS QWNLGIQKPS AKFEKKDGLE VNASEQAYPL KISSYIDNKT
301: EEEINKQQIK GKYLQSGDVV SIKNRYLGGY LCIKRIQRIT DGLDKKPLII KDYETNINYA
361: INQFYFDVDK IRNEKINQMY QLYVDTSPKA DEELNSLWQV QHVDSLIYSR PTYESVFLIR
421: HVCTGLFLQI TNYGVGLTYD GLKMECQINL KSKKTSNDTI SYSEACKIQS AMNFQVDNYV
481: AQESVVVVCL EETKVAVQRK SQKQNIERAT FLFKQTSQDL SKISFRLNSL QEYLIKFYIF
541: LQDWGVVKSI EQNQQNQEEK RKYEYYEAFN NQKSLFDEIL QLFQTLDNLK MYLTNEGKPQ
601: SNEQLQQKQK ALMDNDIINL LFAIQRLCNC MIYGNLRENN KTIQEKSPSK IAKMKLDPIV
661: TQTQKINCIQ EIYSLLSLCV QSNPETSNYV LSLEMNKESI LDFLLQQLKH QREHVSKLIK
721: ESVRYTDMSD TKASIKKWVN ELQPLTEDNI EDQALYIEIL SLMMIDPYEN PNSLCQDSCR
781: RLLFGTRRKP DSSLPFQKAL IALDIYEENQ NYYPVVQFSP KREKGMLLQL SHQFGQNNPT
841: FCQLYLRFVE RQIKVAQRFI TRRPPLVDVT IDFFTTEALK ENQLVKQEDL KTVMPIFLKY
901: ENYLMNVMDL YSSLCKGRNQ KSIKCLMKNC FLNEKFLEIC LKRQQNIKTE LRFERTLIEL
961: FCNLYLDIDP LIKVSQFDNK CYLNDDLDQF DIQNQSGVYF YENNATKQLK RNEEYQKFLN
1021: QKEAKAEHQY MKLYASKMLS RKQINDVRIY YLEIFTQIDY PDHFRVQEFS GNLLQTQKST
1081: INQINIDYKR LAYYQLQYFL GILQIVKNSI DLGYNQLDEN QRIFSILPNI FVALILQQRP
1141: DNKIHKFKEN ENFESNLYKL SQSIEKNVWV TTYLPTAQQL QEQRKSKHKK QDKSSKQSEQ
1201: IIRQDIQFQR NWILQFLIWT FQYCTDDLLK MKIYLEGLQI LKIFGFLKLN LQILEFLFSK
1261: QQLNESNLSS PSSRDLDQFE FNNNEIDNNI QEEQIKKQKT PAQKAIFNVF KEPDGNRFSA
1321: LLFSCLLSSE KRNKLNEELL QILIDNFHAP KNSTNEIKEV EIIDNLMELK YFSIINGNSN
1381: TVQIISPKEA QILTKRATKY IQNSKRRKNA QKRVTSFDSL KNYQSKIIEQ FEQFFKPNSQ
1441: EVQYLKSFQN IVRNAGVHLV FLQFLVKPQN ICSTPDIVQF YKKLILFFEY FTKDNETNIA
1501: ILAQNEYLYK LLDIIQVDQQ DAEDWYYVPI KITKLVVQLL STIPVSEHDN FIINVFERIE
1561: KLGAELMQSE EFFVNAFSLR DVYFERKVTP RKKHLDAVAY FSLIQYLRIL RSLTKTFETP
1621: AEQSPLNKHL ILSSILKNDF LRIVLEPVNY YKKLLVPGQE QEEQNGTDSL YYHRIKLHAQ
1681: LIILITDCCQ YYRLGIQEMQ RIILYEQLKS ILLNSNSEYI VKRAYLQCLF ELYINQAKEG
1741: EFMNDTVESD EVRDILSRII IPELDQKQIC KFLEGLAKLI NQDKNKKVTQ KDLREQIARQ
1801: KRNYFEKRLS IDSTSEKEIG ILRDCSEFWT YLRKNVYTYD EMKDRIDIEN PENSNLSDEF
1861: AIIKQNVQKI KEIFNVLERD FRVKKEDLDL DDYRELIISI EEIIPQRKIT KFGQNFRIGF
1921: IQDKNTDKLL FDKYDTLKED QNGEKKLQEQ DNVQRIENPF KRNFKIYLIR YKVNILQFCY
1981: YIEKSSSELT DQEKSRKIVK TCNVYKQYIL LKDIENIYQT DVARIKNQES VNNRNKQFVD
2041: WELFKQAMRE SFERKFNANI AQQQIQAYQR QQDSLDSLKK DFSLSTIRLI AKYYKKLGGQ
2101: LELNGNLISE DVQIELLIKT LEKQQTNVFN LDNLKDFLKK CQEIFLNKEI YLIKLCRIFL
2161: QLKRPTQDEI DSLTEAKDED SKQFVRDKKE TYVKFQRAMA DGQLDILALE MLNQTDDDQQ
2221: KIEALSFLIH LLDYGNEYVQ KKFYKLLKEE HVKQKFLVFL RGFFLIDLDV RIKELELTNG
2281: DNTEYKLLCL KVLQLLQALC ENVNMEFQRF LVFQYDDDSY QANINIVNEV AGLLADLLEK
2341: GQRVFYKLQE IYRQALESLV EFSTGYVENK KELCKNARLF TLLNSILQKQ DLQNFSSLYK
2401: ENRMILKEKQ QMNQTLDEDI VLDGEGIATN EGKKKYSSYQ TLQSFIKLLL LLTQGRSDIQ
2461: SLEFILKTVD ITILIRISKS IYEERIKPKQ RNIILDNICD ESETGNHRHC TNSLCHFGLR
2521: TDEDNMLIQT GFNIFIICLK LSEHFTQDSQ LELFKFDEEQ EEQEDLLDLD DFQEEELQKK
2581: KTLSNQKILP INPGSKYDYN QDEGDGLLPG GDPKLENSSL KKIFLDVQND KSYQFDRTQR
2641: FFKFYRQFTG RIEIQNEFNQ LEKVFFQKPF VCNFITPNIK QHLIYEINRE TDEDRMLGLI
2701: EYSEFYQVQM RHSQYINNRK VMHFGAVYWR LLKDVSFLLC LIIVVLLIFM HDTVINSKIG
2761: SNTEAPEDQN VTSGESFVSY LNNIITIVQL VLNLIIVFFC AIERYPISIT YNRGQTNAKR
2821: VQILKKEAGF QISWLTMKYY SLIGYFESEF QEEKVNQSSI KKLILVIFFD FDNFYNICIF
2881: GLTVYAFFNP YIYAILLLDI VKRSEDLQNI IRSITSNGRN LAIFSFLGLI GLLIYAIIAF
2941: SNFDQMFDDE SGVYGQTFIL AVTSTINFGL RNGGGIGESL TKYPDAYDDP TLYWGRYFFD
3001: FTFFIIFNIL FIQIIFGIIL DTFGELRDER QALVKEIEGK CFICSQDKND IDTKGTKGWH
3061: YHIYLEHSVY HMLYYIIYIK NKDPNDCNAL EKYVNKCIQE KETKFFPFGR ALQIESQEGD
3121: QDQTEKQ