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| Accession Number: | Q13454 |
| Protein Name: | Tumor suppressor candidate 3 |
| Length: | 348 |
| Molecular Weight: | 39676.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 5 |
| Location1 / Topology2 / Orientation3: | Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
| Substrate | magnesium(2+), copper(2+), iron(2+), manganese(2+) |
Cross database links:
| RefSeq: | NP_006756.2 NP_839952.1 |
|---|---|
| Entrez Gene ID: | 7991 |
| Pfam: | PF04756 PF00085 |
| OMIM: |
601385 gene 611093 phenotype |
| KEGG: | hsa:7991 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0008250
C:oligosaccharyltransferase complex
GO:0045454
P:cell redox homeostasis
GO:0018279
P:protein amino acid N-linked glycosylation v...
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References (5)[1] “Structure and methylation-associated silencing of a gene within a homozygously deleted region of human chromosome band 8p22.” Macgrogan D.et.al. 8661104 [2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [3] “Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.” Kelleher D.J.et.al. 12887896 | |
| Structure: | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MGARGAPSRR RQAGRRLRYL PTGSFPFLLL LLLLCIQLGG GQKKKENLLA EKVEQLMEWS 61: SRRSIFRMNG DKFRKFIKAP PRNYSMIVMF TALQPQRQCS VCRQANEEYQ ILANSWRYSS 121: AFCNKLFFSM VDYDEGTDVF QQLNMNSAPT FMHFPPKGRP KRADTFDLQR IGFAAEQLAK 181: WIADRTDVHI RVFRPPNYSG TIALALLVSL VGGLLYLRRN NLEFIYNKTG WAMVSLCIVF 241: AMTSGQMWNH IRGPPYAHKN PHNGQVSYIH GSSQAQFVAE SHIILVLNAA ITMGMVLLNE 301: AATSKGDVGK RRIICLVGLG LVVFFFSFLL SIFRSKYHGY PYSDLDFE