TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.A.76.1.1









Magnesium transporter, MagT1 (Goytain and Quamme, 2005; Schmitz et al., 2007; Zhou and Clapham, 2009).  As of 2018, the function of this protein as a Mg2+ transporter was under debate (Schäffers et al. 2018).

Eukaryota
Metazoa
MagT1 of Homo sapiens (Q9H0U3)
1.A.76.1.2









Mg2+ transporter; also called Tumor suppressor candidate 3 isoform a, Tusc3a (69% identity with MagT1) (Zhou and Clapham, 2009).

Eukaryota
Metazoa
Tusc3a of Homo sapiens (Q13454)
1.A.76.1.3









Magnesium transporter protein 1 (MagT1) with a thioredoxin domain (residues 50 - 150) and an Ost3/Ost6 domain (residues 160 - 310 with 4 TMSs).

Eukaryota
Metazoa
MagT1 of Danio rerio
1.A.76.1.4









Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3

Eukaryota
Dictyosteliida
Ost3 of Dictyostelium discoideum
1.A.76.1.5









Ubiquitin conjugating enzyme of 345 aas with 4 C-terminal TMSs

Eukaryota
Intramacronucleata
Ubiquitin conjugating enzyme of Oxytricha trifallax
1.A.76.1.7









Putative magnesium transport protein of 354 aas and 4 C-terminal TMSs.

Eukaryota
Oomycetes
MagT1 homologue of Albugo laibachii
1.A.76.1.8









Glycosyl transferase, Ost3 of 350 aas and 4 TMSs.  This protein is a subunit of the yeast oligosaccharyltransferase complex involved in N-glycosylation (Wild et al. 2018). It is not the catalytic subunit (see TC# 9.B.142.3.14).

Eukaryota
Fungi
Ost3 of Saccharomyces cerevisiae
1.A.76.1.9









Ost6-like protein of 332 aas and 4 TMSs.

Eukaryota
Fungi
Ost6 of Saccharomyces cerevisiae (Baker's yeast)
1.A.76.1.10









Ost3/Ost6 homologue of 334 aas and 5 TMSs

Eukaryota
Viridiplantae
Ost3-like protein of Chlamydomonas reinhardtii (Chlamydomonas smithii)
1.A.76.1.11









Uncharacterized protein of 277 aas

Eukaryota
Reticulomyxidae
UP of Reticulomyxa filosa
1.A.76.1.12









Uncharacterized protein of 362 aas

Eukaryota
Heterolobosea
UP of Naegleria gruberi (Amoeba)
1.A.76.1.13









Uncharacterized protein of 328 aas and 7 (or 5) TMSs

Eukaryota
Fungi
UP of Tetrapisispora blattae (Yeast) (Kluyveromyces blattae)
1.A.76.1.14









Mg2+ transporter, MagT1 homologue of 331 aas

Eukaryota
Fungi
MagT1 homologue of Pyronema omphalodes
1.A.76.2.1









Oligosaccharyltransferase complex/magnesium transporter family protein of 173 aas and 3 or 4 TMSs. The proteins in this family are part of a complex of eight ER proteins that transfers core oligosaccharide from dolichol carrier to Asn-X-Ser/Thr motifs. This family includes both OST3 and OST6, each of which contains four predicted transmembrane helices. Disruption of OST3 and OST6 leads to a defect in the assembly of the complex. Hence, the function of these genes seems to be essential for recruiting a fully active complex necessary for efficient N-glycosylation.

Eukaryota
Viridiplantae
Uncharacterized protein of Arabidopsis thaliana (Mouse-ear cress)
1.A.76.2.2









Uncharacterized protein of 148 aas and 3 TMSs

Eukaryota
Hexamitidae
UP of Giardia intestinalis (Giardia lamblia)
1.A.76.2.3









Uncharacterized protein of 159 aas and 3 TMSs

Eukaryota
Bangiophyceae
UP of Cyanidioschyzon merolae
1.A.76.2.4









Uncharacterized protein of 433 aas with 3 N-terminal TMSs.

Eukaryota
Dictyosteliida
UP of Dictyostelium discoideum (Slime mold)
1.A.76.2.5









Oligosaccharyl transferase complex subunit, EgrG of 144 aas and 3 TMSs.

Eukaryota
Metazoa
OST3 family member of Echinococcus granulosus (Hydatid tapeworm)
1.A.76.2.6









OST3/OST6 superfamily protein of 158 aas and 3 TMSs.

Eukaryota
Trichomonadida
OST3 family protein of 158 aas
1.A.76.2.7









OST3/OST6 Family protein of 159 aas and 3 TMSs.

Eukaryota
Trichomonadida
OST3 homologue of Trichomonas vaginalis
1.A.76.2.8









Oligosaccharidyl transferase DS2 of 173 aas and 4 TMSs

Eukaryota
Metazoa
DS2 of Loa loa (Eye worm) (Filaria loa)