TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.B.55.1.1









The β-barrel porin with a superhelical domain containing tetratricopeptide repeats, PgaA or YcdS; exports (deacetylated) poly β-1,6-N-acetyl glucosamine (PGA), a biofilm adhesin that may also play a role in immune evasion (Itoh et al., 2008; Cerca and Jefferson 2008).

Bacteria
Proteobacteria
PgaA of E. coli (P69434)
1.B.55.1.2









PgaA homologue

Bacteria
Proteobacteria
PgaA homologue of Burkholderia cepacia
1.B.55.1.3









PgaA homologue

Bacteria
Proteobacteria
PgaA homologue of Neisseria wadsworthii
1.B.55.2.1









Putative porin of 604 aas

Bacteria
Planctomycetes
Porin of Blastopirellula marina
1.B.55.2.2









Uncharacterized protein of 555 aas and 20 predicted beta strands with an N-terminal TMS.

Bacteria
Nitrospirae
UP of Candidatus Nitroospira defluvii
1.B.55.2.3









TRP-repeat containing protein of 492 aas and 16 predicted beta strands.

Bacteria
Proteobacteria
Trp repeat protein of Geobacter daltonii
1.B.55.3.1









Cellulose synthase operon, protein C of 1157 aas and up to 18 C-terminal (720 - 1157 aas) β-strands with a single N-terminal α-TMS, BcsC or YhjL (Zogaj et al. 2001). Translocation across the outer membrane occurs through the BcsC porin, which extends into the periplasm via 19 tetra-tricopeptide repeats (TPR). Acheson et al. 2019 presented the crystal structure of a truncated BcsC, encompassing the last TPR repeat and the complete outer membrane channel domain, revealing a 16-stranded, β barrel pore architecture. The pore is blocked by an extracellular gating loop, while the extended C terminus inserts deeply into the channel and positions a conserved Trp residue near its extracellular exit. The channel is lined with hydrophilic and aromatic residues suggesting a mechanism for facilitated cellulose diffusion based on aromatic stacking and hydrogen bonding (Acheson et al. 2019).

Bacteria
Proteobacteria
BcsC of E. coli
1.B.55.3.2









Uncharacterized protein of 963 aas

Bacteria
Nitrospirae
UP of Leptospirillum ferriphilum