1.B.90. The Putative Trichomonas Porin-1 (T-Porin-1) Family.
This family of putative porins is believed to be present in hydrogenosomes of Trichomonas species (Rada et al. 2011). The protein from T. vaginalis is predicted to have 16 transmembrane β-strands. Many aspects of hydrogenosomes have been reviewed including an overview of hydrogenosome biogenesis, hydrogenosomal protein import, and the relationship between the peculiar structure of membrane translocases and its low inner membrane potential due to the lack of respiratory complexes (Tachezy et al. 2022). This review also summarizes the current state of knowledge on energy metabolism, the oxygen defense system, and iron/sulfur cluster assembly.
References associated with 1.B.90 family:
Rada, P., P. Doležal, P.L. Jedelský, D. Bursac, A.J. Perry, M. Šedinová, K. Smíšková, M. Novotný, N.C. Beltrán, I. Hrdý, T. Lithgow, and J. Tachezy. (2011). The core components of organelle biogenesis and membrane transport in the hydrogenosomes of Trichomonas vaginalis. PLoS One 6: e24428. 21935410
Tachezy, J., A. Makki, and I. Hrdý. (2022). The hydrogenosome of Trichomonas vaginalis. J Eukaryot Microbiol 69: e12922. 35567536