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| Accession Number: | O35633 |
| Protein Name: | VGAT |
| Length: | 525 |
| Molecular Weight: | 57381.00 |
| Species: | Mus musculus (Mouse) [10090] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cytoplasmic vesicle membrane1 / Multi-pass membrane protein2 |
| Substrate | gamma-aminobutyric acid, glycine |
Cross database links:
| RefSeq: | NP_033534.2 |
|---|---|
| Entrez Gene ID: | 22348 |
| Pfam: | PF01490 |
| KEGG: | mmu:22348 |
Gene Ontology
GO:0030659
C:cytoplasmic vesicle membrane
GO:0060077
C:inhibitory synapse
GO:0005887
C:integral to plasma membrane
GO:0015495
F:gamma-aminobutyric acid:hydrogen symporter ...
GO:0015187
F:glycine transmembrane transporter activity
GO:0015816
P:glycine transport
GO:0006836
P:neurotransmitter transport
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References (5)[1] “Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases.” Sagne C.et.al. 9395291 [2] “Mouse vesicular GABA transporter gene: genomic organization, transcriptional regulation and chromosomal localization.” Ebihara S.et.al. 12573541 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MATLLRSKLT NVATSVSNKS QAKVSGMFAR MGFQAATDEE AVGFAHCDDL DFEHRQGLQM 61: DILKSEGEPC GDEGAEAPVE GDIHYQRGGA PLPPSGSKDQ AVGAGGEFGG HDKPKITAWE 121: AGWNVTNAIQ GMFVLGLPYA ILHGGYLGLF LIIFAAVVCC YTGKILIACL YEENEDGEVV 181: RVRDSYVAIA NACCAPRFPT LGGRVVNVAQ IIELVMTCIL YVVVSGNLMY NSFPGLPVSQ 241: KSWSIIATAV LLPCAFLKNL KAVSKFSLLC TLAHFVINIL VIAYCLSRAR DWAWEKVKFY 301: IDVKKFPISI GIIVFSYTSQ IFLPSLEGNM QQPSEFHCMM NWTHIAACVL KGLFALVAYL 361: TWADETKEVI TDNLPGSIRA VVNLFLVAKA LLSYPLPFFA AVEVLEKSLF QEGSRAFFPA 421: CYGGDGRLKS WGLTLRCALV VFTLLMAIYV PHFALLMGLT GSLTGAGLCF LLPSLFHLRL 481: LWRKLLWHQV FFDVAIFVIG GICSVSGFVH SLEGLIEAYR TNAED