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2.A.18.6.12
Solute carrier family 38, member 8, SLC38A8, expressed only in the eye.  This protein is probably a Na+/H+-dependent amino acid (glutamine) transporter which when defective, gives rise to foveal hypoplasia associated with congenital nystagmus and reduced visual acuity, FHONDA (Perez et al. 2014). SLC38A8 mutations exhibit  arrest of retinal development at an early stage, resulting in a poorly developed retina with a severe phenotype (Kuht et al. 2020). 

Accession Number:A6NNN8
Protein Name:Putative sodium-coupled neutral amino acid transporter 8
Length:435
Molecular Weight:46731.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

Entrez Gene ID: 146167   
Pfam: PF01490   
KEGG: hsa:146167    hsa:146167   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0006865 P:amino acid transport
GO:0006814 P:sodium ion transport

References (2)

[1] “The sequence and analysis of duplication-rich human chromosome 16.”  Martin J.et.al.   15616553
[2] “The sequence and analysis of duplication-rich human chromosome 16.”  Martin J.et.al.   15616553

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEGQTPGSRG LPEKPHPATA AATLSSMGAV FILMKSALGA GLLNFPWAFS KAGGVVPAFL 
61:	VELVSLVFLI SGLVILGYAA AVSGQATYQG VVRGLCGPAI GKLCEACFLL NLLMISVAFL 
121:	RVIGDQLEKL CDSLLSGTPP APQPWYADQR FTLPLLSVLV ILPLSAPREI AFQKYTSILG 
181:	TLAACYLALV ITVQYYLWPQ GLVRESHPSL SPASWTSVFS VFPTICFGFQ CHEAAVSIYC 
241:	SMRKRSLSHW ALVSVLSLLA CCLIYSLTGV YGFLTFGTEV SADVLMSYPG NDMVIIVARV 
301:	LFAVSIVTVY PIVLFLGRSV MQDFWRRSCL GGWGPSALAD PSGLWVRMPL TILWVTVTLA 
361:	MALFMPDLSE IVSIIGGISS FFIFIFPGLC LICAMGVEPI GPRVKCCLEV WGVVSVLVGT 
421:	FIFGQSTAAA VWEMF