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| Accession Number: | Q99624 |
| Protein Name: | SN1 aka G17 |
| Length: | 504 |
| Molecular Weight: | 55773.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), hydron, alanine, asparagine, glutamine, histidine |
Cross database links:
| RefSeq: | NP_006832.1 |
|---|---|
| Entrez Gene ID: | 10991 |
| Pfam: | PF01490 |
| OMIM: |
604437 gene |
| KEGG: | hsa:10991 hsa:10991 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0015297
F:antiporter activity
GO:0015180
F:L-alanine transmembrane transporter activity
GO:0015182
F:L-asparagine transmembrane transporter acti...
GO:0015186
F:L-glutamine transmembrane transporter activity
GO:0005290
F:L-histidine transmembrane transporter activity
GO:0015293
F:symporter activity
GO:0006867
P:asparagine transport
GO:0006868
P:glutamine transport
GO:0015817
P:histidine transport
GO:0015808
P:L-alanine transport
GO:0006814
P:sodium ion transport
GO:0015182
F:L-asparagine transmembrane transporter activity
GO:0006811
P:ion transport
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References (12)[1] “Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter.” Fei Y.-J.et.al. 10823827 [2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [3] “The full-ORF clone resource of the German cDNA consortium.” Bechtel S.et.al. 17974005 [4] “The DNA sequence, annotation and analysis of human chromosome 3.” Muzny D.M.et.al. 16641997 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [6] “The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes.” Lerman M.I.et.al. 11085536 [7] “Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter.” Fei Y.-J.et.al. 10823827 [8] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [9] “The full-ORF clone resource of the German cDNA consortium.” Bechtel S.et.al. 17974005 [10] “The DNA sequence, annotation and analysis of human chromosome 3.” Muzny D.M.et.al. 16641997 [11] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [12] “The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes.” Lerman M.I.et.al. 11085536
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MEAPLQTEMV ELVPNGKHSE GLLPVITPMA GNQRVEDPAR SCMEGKSFLQ KSPSKEPHFT 61: DFEGKTSFGM SVFNLSNAIM GSGILGLAYA MANTGIILFL FLLTAVALLS SYSIHLLLKS 121: SGVVGIRAYE QLGYRAFGTP GKLAAALAIT LQNIGAMSSY LYIIKSELPL VIQTFLNLEE 181: KTSDWYMNGN YLVILVSVTI ILPLALMRQL GYLGYSSGFS LSCMVFFLIA VIYKKFHVPC 241: PLPPNFNNTT GNFSHVEIVK EKVQLQVEPE ASAFCTPSYF TLNSQTAYTI PIMAFAFVCH 301: PEVLPIYTEL KDPSKKKMQH ISNLSIAVMY IMYFLAALFG YLTFYNGVES ELLHTYSKVD 361: PFDVLILCVR VAVLTAVTLT VPIVLFPVRR AIQQMLFPNQ EFSWLRHVLI AVGLLTCINL 421: LVIFAPNILG IFGVIGATSA PFLIFIFPAI FYFRIMPTEK EPARSTPKIL ALCFAMLGFL 481: LMTMSLSFII IDWASGTSRH GGNH