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2.A.18.6.8 Second subtype of system N; glutamine transporter, SN2. Prevalent in liver, but detectable in other tissues. Amino acid uptake is coupled to Na⁺ influx and H⁺ efflux (Nakanishi et al., 2001)
Accession Number:	A2VCW5
Protein Name:	Sodium-coupled neutral amino acid transporter 5
Length:	479
Molecular Weight:	52436.00
Species:	[10116]
Number of TMSs:	11
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	sodium(1+), hydron, glutamine

RefSeq:	NP_620209.1
Entrez Gene ID:	192208
Pfam:	PF01490
KEGG:	rno:192208
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0015187 F:glycine transmembrane transporter activity GO:0015816 P:glycine transport
References (4) [1] “Cloning and functional characterization of a new subtype of the amino acid transport system N.” Nakanishi T.et.al. 11698233 [2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [3] “Amino acid transporter SNAT5 localizes to glial cells in the rat brain.” Cubelos B.et.al. 15390093 [4] “Evidence for allosteric regulation of pH-sensitive System A (SNAT2) and System N (SNAT5) amino acid transporter activity involving a conserved histidine residue.” Baird F.E.et.al. 16629640

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MAISCAVGME MQEPKMNGTL STGAAAGYRQ EREGFLPTTH GPAPGRKPVQ FLDFEGKTSF 
61:	GMSVFNLSNA IMGSGILGLA YAMAHTGVIF FLALLLCIAL LSSYSIHLLL TCASVVGIRA 
121:	YEQLGQRAFG PAGKVVVAII ICLHNVGAMS SYLFIIKSEL PLVIGTFLHM DPEGDWFLKG 
181:	NLLIILVSLL IILPLALMKH LGYLGYTSSL SLTCMLFFLI SVIYKKFQLG CVVSHNDTVV 
241:	ESEPAPLQAF NSSCEAKLFT VDSQMSYTVP IMAFAFVCHP EVLPIYTELC CPTQRRMQAV 
301:	ANMSIGAMFI MYGLTATFGY LTFYSTVKAE MLEMYTQEDL LILCVRLAVL LAVTLTVPVV 
361:	LFPIRRALQQ LLFPSKAFSW PRHVAIALIL LILVNILVIC VPTIRDIFGF IGSTSAPSLI 
421:	FILPSVFYLR IVPADMEPLF SWPKIQALCF GVLGVLFMAI SLGFMFANWA TGQSRMSGH

2.A.18.6.8
Second subtype of system N; glutamine transporter, SN2. Prevalent in liver, but detectable in other tissues. Amino acid uptake is coupled to Na⁺ influx and H⁺ efflux (Nakanishi et al., 2001)

Cross database links:

Gene Ontology

References (4)

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2.A.18.6.8Second subtype of system N; glutamine transporter, SN2. Prevalent in liver, but detectable in other tissues. Amino acid uptake is coupled to Na+ influx and H+ efflux (Nakanishi et al., 2001)

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

2.A.18.6.8
Second subtype of system N; glutamine transporter, SN2. Prevalent in liver, but detectable in other tissues. Amino acid uptake is coupled to Na⁺ influx and H⁺ efflux (Nakanishi et al., 2001)