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2.A.3.10.13
Dicarboxylic amino acid permease

Accession Number:P53388
Protein Name:Dip5 aka YPL265W
Length:608
Molecular Weight:68097.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate aspartic acid, glutamic acid

Cross database links:

DIP: DIP-5540N
RefSeq: NP_015058.1   
Entrez Gene ID: 855863   
Pfam: PF00324   
KEGG: sce:YPL265W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0042802 F:identical protein binding
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (7)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.”  Bussey H.et.al.   9169875
[2] “Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.”  Regenberg B.et.al.   10654085
[3] “Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae.”  Ficarro S.B.et.al.   11875433
[4] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[5] “Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.”  Gruhler A.et.al.   15665377
[6] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[7] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MKMPLKKMFT STSPRNSSSL DSDHDAYYSK QNPDNFPVKE QEIYNIDLEE NNVSSRSSTS 
61:	TSPSARDDSF AVPDGKDENT RLRKDLKARH ISMIAIGGSL GTGLLIGTGT ALLTGGPVAM 
121:	LIAYAFVGLL VFYTMACLGE MASYIPLDGF TSYASRYVDP ALGFAIGYTY LFKYFILPPN 
181:	QLTAAALVIQ YWISRDRVNP GVWITIFLVV IVAINVVGVK FFGEFEFWLS SFKVMVMLGL 
241:	ILLLFIIMLG GGPNHDRLGF RYWRDPGAFK EYSTAITGGK GKFVSFVAVF VYSLFSYTGI 
301:	ELTGIVCSEA ENPRKSVPKA IKLTVYRIIV FYLCTVFLLG MCVAYNDPRL LSTKGKSMSA 
361:	AASPFVVAIQ NSGIEVLPHI FNACVLVFVF SACNSDLYVS SRNLYALAID GKAPKIFAKT 
421:	SRWGVPYNAL ILSVLFCGLA YMNVSSGSAK IFNYFVNVVS MFGILSWITI LIVYIYFDKA 
481:	CRAQGIDKSK FAYVAPGQRY GAYFALFFCI LIALIKNFTV FLGHKFDYKT FITGYIGLPV 
541:	YIISWAGYKL IYKTKVIKST DVDLYTFKEI YDREEEEGRM KDQEKEERLK SNGKNMEWFY 
601:	EKFLGNIF