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2.A.31.2.5
Kidney apical membrane anion exchanger of β-intercalated cells, AE4a

Accession Number:Q9GKY1
Protein Name:Anion exchange protein 4
Length:955
Molecular Weight:105033.00
Species: [9986]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Apical cell membrane1 / Multi-pass membrane protein2
Substrate anions

Cross database links:

RefSeq: NP_001075474.1   
Entrez Gene ID: 100008621   
Pfam: PF07565    PF00955   

Gene Ontology

GO:0016324 C:apical plasma membrane
GO:0016021 C:integral to membrane
GO:0005452 F:inorganic anion exchanger activity
GO:0006820 P:anion transport

References (1)

[1] “A new member of the HCO3-transporter superfamily is an apical anion exchanger of beta-intercalated cells in the kidney.”  Tsuganezawa H.et.al.   11102437

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MKLPGQEELE AACACENVPV GQLDSGPSSG PCPDDPSDTG SRELGPPEDP PLFLQLNELL 
61:	GWPQTLEWRE MGRWVLFEEK LEVDAGRWSA PHVPTLALPS LQNLRSLLAE GLVLLDCPAQ 
121:	NLLELVEQVT RVESLSPELR GQLQALLLQR PQHHTQTTGS RPCWGPAQSR KAAHNKEAPM 
181:	QQQCQSPLRQ KLPPGAEAGA VLAGELGFLA QPLAAFVRLR DPVWLGPLTE VPLPSRFFCL 
241:	LLGPPMLGKG YHELGRAAAV LLSDPHFQWS VRRASNLHDL LTALDAFLEE VTVLPPGRWD 
301:	PTARIPPPRC LPSRHKRPPL HLQKVKGLSV PHRTQAEDRH RNGPLAPSPE LQRTGRLFGG 
361:	LVQDVRRKAS WYPSDFSDAL HPQCVSAVLY IYLATVTNAI TFGGLLGDAT DGAQGVLESL 
421:	LGTAVAGAAF CLMAGQPLTV LSSTGPVLVF ERLLFAFCRD YSLDYLPFRL WVGIWVAVFC 
481:	LALVATEASV LVRYFTRFTE EGFCALISLI FIYDAVGKML NLAHAYPIQR PGSLAYGCLC 
541:	QFPGPGGNES QWTRPRPQSR DDLLSVDLGL VNASLLPPHE CVQQGGYPRG PGCHTVPDIA 
601:	FFSLLLFLTS FLFAIALKHM KTSRFFPSVV RKVLSDFSSI LAILLGCGLD ALLGLAMPKL 
661:	MVPREFKPTL PGRGWLVPPF GANPWWLSVA AALPALLLSI LIFMDQQITA VILNRVEYRL 
721:	RKGAGFHLDL FCVALLMLLT SVLGLPWYVS ATVLSLAHMD SLRRESRACA PGEPHSFLGI 
781:	REQRLTGLAV FTLTGVSIFL APVLKFIPMP VLYGIFLYMG VAALSSIQFM KRVQLMLMPA 
841:	KHQPDLLLLR HVPLSRVHLF TAIQLACLGL LWIIKSTPAA IIFPLMLLGL VGVRKALEWV 
901:	FSPQELLWLD ELMPEEERNV PEKGLEPGHS FSGSDSEDSE LMYQPKAPEI NISVN