TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
2.A.32.1.1









Silicon transporter of 548 aas and 10 probable TMSs in a 2 + 3 + 2 + 3 TMS arrangement. It has a conserved aa motif, CMLD. Hydropathy profiles suggest that CMLD occupies a position between two TMSs. These two TMSs are candidates for a role of the channel through which transport of silicic acid occurs (Shcherbakova et al. 2006).

Eukaryota
Bacillariophyta
Sit1 of Cylindrotheca fusiformis (marine diatom)
2.A.32.1.2









Silicon transporter, SIT1, of 546 aas and 10 probable TMSs in a 2  + 3 + 2 + 3 TMS arrangement.

Eukaryota
Bacillariophyta
SIT1 of Nitzschia alba (marine diatom)
2.A.32.1.3









Silicic acid transport protein, SIT, of 571 aas and 12 or 13 TMSs in a possible 1 + 2 + 3 + 2 + 3 +2 TMS arrangement.

Eukaryota
Bacillariophyta
SIT of Ulnaria acus
2.A.32.1.4









Silicic acid transporter, Sit1, of 503 aas and 10 TMSs in a 2 + 3 + 2 + 3 TMS arrangement (Durak et al. 2016).

Eukaryota
Haptophyta
Sit1 of Prymnesium neolepis
2.A.32.1.5









Silicon transporter alpha, Sit, of 527 aas and 10 TMSs in a 2 + 3 + 2 + 3 TMS arrangement.

Eukaryota
Sit of Helgoeca nana
2.A.32.1.6









Putative silicon transporter of 225 aas, Sit, with proably 5 or 6 TMSs in a 2 + 3 or 2 + 3 + 1 TMS arrangement.  This sequence (which could be a fragment) shows about the same percent identity with both halves of the longer proteins listed in TC#s 2.A.32.1.1 - 1.5.

Eukaryota
Bacillariophyta
Sit of Fragilaria crotonensis
2.A.32.1.7









Silicon transporter, Sit, of 477 aas and 10 TMSs in a 2 + 3 + 2 + 3 TMS arrangement.

Eukaryota
Sit of Ochromonas distigma
2.A.32.1.8









Uncharacterized protein of 407 aas with 5 TMSs in a 2 + 3 TMS arrangement (residues 1 - 210) followed by a 200 residue hydrophilic domain. Residues 1 - 210 show about equal sequence similarity with the two halves of all of the full length sequences (2.A.32.1.1 - 1.5 and 1.7). The N-terminal half of the protein seems to be a half transporter and may function as a dimer in the membrane.

Eukaryota
Metazoa, Chordata
UP of Styela clava
2.A.32.1.9









Uncharacterized protein of 352 aas and 5 N-terminal TMSs (residues 1 - 210) followed by a 150 residue hydrophilic domain, similar in sequence to that of TC# 2.A.32.1.8.

Eukaryota
Metazoa, Chordata
UP of Phallusia mammillata
2.A.32.1.10









Uncharacterized half transporter of 361 aas with 5 TMSs in a 2 + 3 TMS arrangement followed by a hydrophilic domain similar in sequence to those for 2.A.32.1.8 and 9.

Eukaryota
Metazoa, Chordata
UP of Ciona intestinalis (vase tunicate)
2.A.32.1.11









Silicon transporter-like 1, Sit-L, of 368 aas and 5 (2 + 3) TMSs followed by a hydrophilic domain.

Eukaryota
Cercozoa
Sit-L of Phaeodaria sp.
2.A.32.1.13









Uncharacterized protein of 225 aas and 5 TMSs in a 2 + 3 TMS arrangement.

Bacteria
Cyanobacteriota
UP of Cyanobium sp.
2.A.32.1.14









Uncharacterized protein of 222 aas and 5 TMSs in a 2 + 3 TMS arrangement.

Bacteria
Cyanobacteriota
UP of Synechococcus sp
2.A.32.1.15









Uncharacterized protein of 525 aas and 5 TMSs in a 2 + 3 TMS arrangement, with two moderately hydrophobic peaks preceeding these TMSs.

Bacteria
Pseudomonadota
UP of Gammaproteobacteria bacterium (marine metagenome)
2.A.32.1.16









Putative silicon transporter of 1555 aas with ~30 TMSs including 6 repeats of the usual 2 + 3 TMS repeat, characteristic of this family.

Eukaryota
Bacillariophyta
Silicon transporter of Nitzschia inconspicua
2.A.32.1.17









Uncharacterized protein of 542 aas and 4 - 6 TMSs in a 2 + 2, 2 + 3 or 3 + 3 TMS arrangement. The first TMS of the first set of 3, and the last TMS in the second set of 3 show very weak hydrophobicity.

Bacteria
Armatimonadota
UP of Armatimonadetes bacterium (aquatic metagenome)