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|---|---|
| Accession Number: | Q552S0 |
| Protein Name: | Sodium/hydrogen exchanger 1 |
| Length: | 674 |
| Molecular Weight: | 75521.00 |
| Species: | Dictyostelium discoideum (Slime mold) [44689] |
| Number of TMSs: | 13 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), hydron |
Cross database links:
| Entrez Gene ID: | 8620198 |
|---|---|
| Pfam: | PF00999 |
| KEGG: | ddi:DDB_G027571 |
Gene Ontology
GO:0005737
C:cytoplasm
GO:0016021
C:integral to membrane
GO:0031256
C:leading edge membrane
GO:0015385
F:sodium:hydrogen antiporter activity
GO:0051453
P:regulation of intracellular pH
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References (4)[1] “Sequence and analysis of chromosome 2 of Dictyostelium discoideum.” Gloeckner G.et.al. 12097910 [2] “The genome of the social amoeba Dictyostelium discoideum.” Eichinger L.et.al. 15875012 [3] “A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis.” Patel H.et.al. 15851518 [4] “Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains.” Carilla-Latorre S.et.al. 18590548
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MKLNKSYILI VVLLLSLFYS SVSSTKTTLI KSNNHYNSDN SNNDNKNINI NNNNDGDGDD 61: DDDNNKILIT PENQNHLIHD IGIDSSSTEI LFGSSSNSGS CGEKNNTKQN ALANQREANT 121: IIFIIMLILT GSVLIVYFII SLDIPFVPES VAVVTYGIIL GIVFRFFYSD IVNHVVSFEP 181: ENFFLFILPT IIFETGYSLH KTDFFNNIGP ILMFAVFGTI ITFLVVGFGI YIVGYFGVSI 241: ALSLKDSFAF GSIISSTDPV CTLAIFQALN VDPMLYILVL GESILNDATS MMLYSVVEDT 301: STRDIIISCA MFTVVAIGSV ILGVVMALLL SLILKWINIG KFPALETIFM VMFSYMSYVL 361: AGALDISGVL AVFFFGITLN QYGAYSLSPY TKLTSGQLFR TAAFISETFL FLYFGLSLTA 421: HEFKFDLGLF SWSILFTCLA RAISVFPMCF LLNKFLKTKI PWVIQVAIWF AGLRGAFAFS 481: LSLDYISEDE HMNAYIRTNT LLVVVFTIFV FGMGTYPLLR VLGIKTSQTD QSLDNISKPM 541: SKQTKQKDRT KLYESFDDKY FKPWFRKRVP PLANEAIEIF EKMVIQSSHD HELDSNPLRF 601: DDDEEDDDDE DLDFDSDLDL NININTDSIH QSDNNNNDNG NNNNNNNNII INNNSQHHSN 661: DGSNNKNNDT LPLI